Agrawal Prachi G, Joshi Rajesh, Kharkar Vidya D, Bhaskar M V
Department of Skin and VD, Gordhandas Sunderdas Medical College and King Edward Memorial Hospital (GSMC and KEMH), Mumbai, Maharashtra, India.
Department of Pediatrics, Bai Jerbai Wadia Children's Hospital, Mumbai, Maharashtra, India.
Indian J Sex Transm Dis AIDS. 2014 Jul-Dec;35(2):143-5. doi: 10.4103/0253-7184.142411.
Congenital syphilis is a severe, disabling infection that occurs due to the transmission of Treponema pallidum across the placenta during pregnancy or from contact with an infectious genital lesion during delivery. However, its early diagnosis is often difficult because more than half of the affected infants are asymptomatic, and the signs in symptomatic infants may be subtle and nonspecific. Although its incidence is declining, this long-forgotten disease continues to affect pregnant women, resulting in considerable perinatal morbidity and mortality. We hereby report a case of a 2-month-old infant with early congenital syphilis presenting with joint swellings and Parrot's pseudoparalysis, a comparative rarity in the present scenario. The report also stresses upon the importance of implementing the Centres for Disease Control and Prevention recommendation that all the pregnant women should be screened for syphilis in the first antenatal visit in the first trimester and again in late pregnancy.
先天性梅毒是一种严重的、致残性感染，它是由于孕期梅毒螺旋体经胎盘传播，或分娩时接触感染性生殖器损害所致。然而，其早期诊断往往困难，因为超过半数的患病婴儿无症状，而有症状婴儿的体征可能不明显且无特异性。尽管其发病率在下降，但这种被长期遗忘的疾病仍继续影响着孕妇，导致相当高的围产期发病率和死亡率。我们在此报告一例2个月大的早期先天性梅毒婴儿病例，该婴儿表现为关节肿胀和帕罗假性瘫痪，在当前情况下较为罕见。该报告还强调了实施疾病控制与预防中心建议的重要性，即所有孕妇应在孕早期首次产前检查时以及妊娠晚期再次接受梅毒筛查。
