Marta Gustavo Nader, William William N, Feher Olavo, Carvalho André Lopes, Kowalski Luiz Paulo
Department of Radiation Oncology, Hospital Sírio-Libanês and Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, Brazil.
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, USA.
Oral Oncol. 2015 Dec;51(12):1069-75. doi: 10.1016/j.oraloncology.2015.10.009. Epub 2015 Oct 27.
There is a lack of data from phase III randomized studies to support an ideal approach for locally advanced oral cavity cancer patients. In general, surgery, radiotherapy and chemotherapy are valid treatment options, and combined approach is usually indicated given poor clinical outcomes with single modality therapy. The aim of this study is to review the current status and future perspectives of induction chemotherapy for locally advanced oral cavity cancer patients.
缺乏来自III期随机研究的数据来支持针对局部晚期口腔癌患者的理想治疗方法。一般来说,手术、放疗和化疗都是有效的治疗选择,鉴于单一模式治疗的临床结果不佳,通常采用联合治疗方法。本研究的目的是回顾局部晚期口腔癌患者诱导化疗的现状和未来前景。