Valencia Lucía, Rodríguez-Pérez Aurelio, Ojeda Nazario, Santana Romen Yone, Morales Laura, Padrón Oto
Department of Anaesthesiology, Hospital Universitario de Gran Canaria Doctor Negrín, Barranco de la Ballena s/n, 35010 Las Palmas de Gran Canaria, Spain.
Department of Anaesthesiology, Hospital Universitario de Gran Canaria Doctor Negrín, Barranco de la Ballena s/n, 35010 Las Palmas de Gran Canaria, Spain.
Anaesth Crit Care Pain Med. 2015 Dec;34(6):345-8. doi: 10.1016/j.accpm.2015.06.008. Epub 2015 Oct 29.
The aim of the present study was to evaluate baseline regional cerebral oxygen saturation (rSO2) values and identify factors influencing preoperative rSO2 in elective minor surgery.
Observational analysis post-hoc.
Observational post-hoc analysis of data for the patient sample (n=50) of a previously conducted clinical trial in patients undergoing tumourectomy for breast cancer or inguinal hernia repair. Exclusion criteria included pre-existing cerebrovascular diseases, anaemia, baseline pulse oximetry <97% and low quality rSO2 sensor signals. Demographic data, comorbidities, and ASA physical status as well as height and weight were collected prospectively from all patients. Baseline rSO2 values were recorded while the patient breathed room air, using the INVOS 5100C monitor™ (Covidien, Dublin, Ireland).
Thirty-seven women (72%) and 13 men (28%) 48 ± 13 years of age were enrolled in this study. Baseline rSO2 was 62.01 ± 10.38%. Baseline rSO2 was significantly different between men (67.6 ± 11.2%) and women (60 ± 9.4%), (P=0.023). There were also differences between baseline rSO2 and ASA physical status (ASA I: 67.6 ± 10.7%, ASA II: 61.6 ± 8.4%, ASA III: 55.8 ± 13.9%, P=0.045). Baseline rSO2 had a positive correlation with body weight (r=0.347, P=0.014) and height (r=0.345, P=0.014). We also found significant differences in baseline rSO2 among patients with and without chronic renal failure (P=0.005). No differences were found in any other studied variables.
Non-modifiable patient characteristics (ASA physical status, sex, chronic renal failure, body weight and height) influence baseline rSO2.
本研究旨在评估择期小手术患者的基线区域脑氧饱和度（rSO2）值，并确定影响术前rSO2的因素。
事后观察性分析。
对先前一项针对乳腺癌肿瘤切除术或腹股沟疝修补术患者的临床试验中患者样本（n = 50）的数据进行事后观察性分析。排除标准包括既往存在的脑血管疾病、贫血、基线脉搏血氧饱和度<97%以及rSO2传感器信号质量差。前瞻性收集所有患者的人口统计学数据、合并症、美国麻醉医师协会（ASA）身体状况以及身高和体重。使用INVOS 5100C监护仪（科惠力公司，都柏林，爱尔兰）在患者呼吸室内空气时记录基线rSO2值。
本研究纳入了37名女性（72%）和13名男性（28%），年龄为48±13岁。基线rSO2为62.01±10.38%。男性（67.6±11.2%）和女性（60±9.4%）的基线rSO2存在显著差异（P = 0.023）。基线rSO2与ASA身体状况之间也存在差异（ASA I：67.6±10.7%，ASA II：61.6±8.4%，ASA III：55.8±13.9%，P = 0.045）。基线rSO2与体重（r = 0.347，P = 0.014）和身高（r = 0.345，P = 0.014）呈正相关。我们还发现有慢性肾衰竭和无慢性肾衰竭患者的基线rSO2存在显著差异（P = 0.005）。在任何其他研究变量中均未发现差异。
不可改变的患者特征（ASA身体状况、性别、慢性肾衰竭、体重和身高）会影响基线rSO2。
