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德国女性子宫肌瘤患病率:一项流行病学研究的数据

Prevalence of uterine myomas in women in Germany: data of an epidemiological study.

作者信息

Ahrendt Hans-Joachim, Tylkoski Heike, Rabe Thomas, Szczes André, Friedrich Cornelia, Roehl Friedrich-Wilhelm, Kitay Ann, Roemer Thomas, Foth Dolores

机构信息

Praxis für Frauenheilkunde und Klinische Forschung, Halberstädter Str. 122, 39112, Magdeburg, Germany.

Praxis für Gynäkologie und Geburtshilfe, Leipziger Straße 45B, 39120, Magdeburg, Germany.

出版信息

Arch Gynecol Obstet. 2016 Jun;293(6):1243-53. doi: 10.1007/s00404-015-3930-8. Epub 2015 Nov 2.

Abstract

PURPOSE

Currently, no reliable data are available concerning the prevalence of uterine myomas in Germany. In this prospective study, we examined the prevalence of myomas in women older than 30 years by means of vaginal ultrasound.

METHODS

2296 women, who consented to the procedure, were examined by means of vaginal ultrasound for the presence of myomas in seven gynaecological outpatient departments in Germany.

PREVALENCE

myomas were detected in 41.6 % of all women. Age dependence: With increasing age, the prevalence of uterine myomas rose from 21.3 % (30-35 years) to 62.8 % (46-50 years). Later, the number of myomas decreased again from 56.1 % (51-55 years) to 29.4 % in women older than 55 years. Menarche/BMI: no correlation could be found between the age at first menstrual period or the body mass index and the occurrence of myomas. Parity: since the group of nulliparous women and the group of women with more than four deliveries stand out by increased occurrence of myomas, a non-linear correlation seems to exist, necessitating more in-depth discussion with regard to age dependency.

CONCLUSIONS

The results of this study suggest that more than 40 % of women over 30 years of age suffered from myomas and more than 50 % of all women in Germany may develop uterine myomas at some time in their life.

摘要

目的

目前,关于德国子宫肌瘤的患病率尚无可靠数据。在这项前瞻性研究中,我们通过阴道超声检查了30岁以上女性子宫肌瘤的患病率。

方法

在德国的七个妇科门诊部门,对2296名同意接受该检查的女性进行了阴道超声检查,以确定是否存在子宫肌瘤。

患病率

在所有女性中,41.6%检测出患有子宫肌瘤。年龄依赖性:随着年龄的增长,子宫肌瘤的患病率从21.3%(30 - 35岁)升至62.8%(46 - 50岁)。之后,肌瘤数量再次下降,从51 - 55岁女性中的56.1%降至55岁以上女性中的29.4%。初潮/体重指数:初潮年龄或体重指数与肌瘤的发生之间未发现相关性。产次:由于未生育女性组和分娩四次以上女性组的肌瘤发生率较高,似乎存在非线性相关性,因此有必要就年龄依赖性进行更深入的讨论。

结论

本研究结果表明,超过40%的30岁以上女性患有肌瘤,德国超过50%的女性一生中可能在某个时候患上子宫肌瘤。

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