Yang Li, Su Chang, Lee Ashley M, Bai Harrison X
Department of Neurology, The Second Xiangya Hospital, Central South University, No. 139 Middle Renmin Road, Changsha, Hunan, 410011, PR China.
Department of Bioengineering, University of Pennsylvania, 210S. 33rd street, Suite 240 Skirkanich Hall, Philadelphia, PA, 19104, USA.
Orphanet J Rare Dis. 2015 Nov 2;10:142. doi: 10.1186/s13023-015-0361-3.
The Chinese researchers have made significant progress in studying rare diseases in the recent years. From 2000 to 2014, 269 out of 1892 clinically relevant original research papers published on high impact journals by Chinese institutions, and 2678 out of 6040 clinical trials conducted by Chinese institutions and registered at ClinicalTrial.gov are focused on rare diseases. The number of research papers and of clinical trials has shown a steady trend of increase. Creating public databases for rare disease will escalate progress in rare disease and enable multicenter studies.
近年来，中国研究人员在罕见病研究方面取得了重大进展。2000年至2014年，中国机构在高影响力期刊上发表的1892篇临床相关原创研究论文中，有269篇聚焦于罕见病；在中国机构开展并在ClinicalTrial.gov注册的6040项临床试验中，有2678项聚焦于罕见病。研究论文和临床试验的数量呈稳步增长趋势。创建罕见病公共数据库将加快罕见病研究进展，并推动多中心研究。
