Ray S, Sanyal S, Ghatak S, Sonar P K, Das S, Khamrui S, Chattopadhyay G
Division of Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244, A. J. C. Bose Road, 700020 Kolkata, West Bengal, India.
Division of Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244, A. J. C. Bose Road, 700020 Kolkata, West Bengal, India.
J Visc Surg. 2016 Feb;153(1):9-13. doi: 10.1016/j.jviscsurg.2015.10.007. Epub 2015 Oct 29.
Delayed hemorrhage, though rare, remains a significant source of morbidity and mortality after pancreaticoduodenectomy (PD). An important cause of this delayed hemorrhage is erosion or pseudoaneurysm formation of the gastroduodenal artery (GDA) by pancreatic enzymes and adjacent intra-abdominal sepsis. So protection of the GDA stump may avoid this devastating complication.
This is a retrospective observational study. All patients, who underwent a PD between August 2007 and December 2014, were included in the study. We used pedicled falciform ligament flap to protect the GDA stump. After PD, pedicled falciform ligament flap was spread widely over the skeletonized hepatic artery including the GDA stump and was fixed to the surrounding retroperitoneal connective tissue. This procedure allowed complete separation of the GDA stump from the pancreatic stump.
We performed 182 cases of PD during the study period. Although, 27 (15%) patients developed pancreatic fistula and six patients developed intra-abdominal abscess, no one experienced hemorrhage due to erosion or pseudoaneurysm formation of the GDA.
The present surgical option seems to be an effective measure for the prevention of erosion and pseudoaneurysm formation of the GDA after PD.
延迟性出血虽罕见,但仍是胰十二指肠切除术(PD)后发病和死亡的重要原因。这种延迟性出血的一个重要原因是胰酶和腹腔内邻近感染导致胃十二指肠动脉(GDA)受到侵蚀或形成假性动脉瘤。因此,保护GDA残端可避免这一致命并发症。
这是一项回顾性观察研究。纳入2007年8月至2014年12月期间接受PD手术的所有患者。我们采用带蒂镰状韧带瓣保护GDA残端。PD术后,将带蒂镰状韧带瓣广泛铺展于包括GDA残端在内的骨骼化肝动脉上,并固定于周围腹膜后结缔组织。该操作使GDA残端与胰腺残端完全分离。
研究期间我们共进行了182例PD手术。尽管有27例(15%)患者发生胰瘘,6例患者发生腹腔内脓肿,但无一例因GDA侵蚀或假性动脉瘤形成而出血。
目前的手术方式似乎是预防PD术后GDA侵蚀和假性动脉瘤形成的有效措施。