Department of Surgical Oncology, Institut Paoli-Calmettes, 232 Boulevard Sainte Marguerite, 13009, Marseille, France.
Department of Surgical Oncology, Institut Paoli-Calmettes, CRCM, Aix-Marseille University, Marseille, France.
Langenbecks Arch Surg. 2022 Feb;407(1):377-382. doi: 10.1007/s00423-021-02345-z. Epub 2021 Nov 23.
This study proposes and details a simple and inexpensive protective technique of wrapping the hepatic and gastroduodenal artery stumps with a peritoneal patch during pancreatoduodenectomy (PD) in order to decrease post-pancreatectomy hemorrhage (PPH).
Among the 85 patients who underwent PD between July 2020 and March 2021, 16 patients with high-risk pancreatic anastomosis received a peritoneal patch. The Updated Alternative Fistula Risk Score (ua-FRS) was calculated. Post-operative pancreatic fistula (POPF) and PPH were diagnosed and graded according to the International Study Group of Pancreatic Surgery. The mortality rate was calculated up to 90 days after PD.
The mean ua-FRS of the 16 patients was 43% (range: 21-63%). Among them, 6 (38%) experienced clinically relevant-POPF, and a PPH was observed in two patients (13%). In these two patients who required re-intervention, the peritoneal patch was remarkably intact, and neither the gastroduodenal stump nor hepatic artery was involved. None of the patients experienced 90-day mortality.
Although the outcomes are encouraging, the evaluation of a larger series to assess the effectiveness of the peritoneal protective patch for arteries in a high-risk pancreatic anastomosis is ongoing.
本研究提出并详细介绍了一种在胰十二指肠切除术(PD)中用腹膜补丁包裹肝胃动脉残端的简单且廉价的保护技术,以降低胰切除术后出血(PPH)的风险。
在 2020 年 7 月至 2021 年 3 月期间接受 PD 的 85 名患者中,有 16 名高危胰腺吻合术患者接受了腹膜补丁。计算了更新的替代瘘管风险评分(ua-FRS)。根据国际胰腺外科研究组的标准,诊断和分级术后胰瘘(POPF)和 PPH。计算 PD 后 90 天内的死亡率。
16 名患者的平均 ua-FRS 为 43%(范围:21-63%)。其中,6 名(38%)患者出现临床相关的 POPF,2 名(13%)患者发生 PPH。在这两名需要再次干预的患者中,腹膜补丁完好无损,胃十二指肠残端和肝动脉均未受累。没有患者在 90 天内死亡。
尽管结果令人鼓舞,但仍在评估更大系列的病例以评估腹膜保护补丁在高危胰腺吻合术中对动脉的有效性。