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儿童盲目与超声引导下经皮肝穿刺活检的并发症

Complications of blind versus ultrasound-guided percutaneous liver biopsy in children.

作者信息

Honar Naser, Jooya Parisa, Haghighat Mahmood, Imanieh Mohammad Hadi, Dehghani Seyed Mohsen, Zahmatkeshan Mozhgan, Javaherizadeh Hazhir

机构信息

Gastroenterohepatology Research Center, Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

Gastroenterohepatology Research Center, Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Arab J Gastroenterol. 2015 Sep-Dec;16(3-4):90-3. doi: 10.1016/j.ajg.2015.09.009. Epub 2015 Oct 30.

Abstract

BACKGROUND AND STUDY AIMS

Liver biopsy is a well-established procedure in the diagnosis and follow-up of liver diseases. Complications of liver biopsy are rare but potentially lethal. The aim of this study was to evaluate the complications of percutaneous liver biopsy and to compare the complications of blind and ultrasound-guided percutaneous liver biopsy in paediatric wards of Nemazee Hospital of Shiraz in the south of Iran.

PATIENT AND METHOD

To complete the questionnaire, registered information of liver biopsies due to different causes in paediatric patients between 2008 and 2012 was retrospectively reviewed. All children aged between 0 and 18years, who underwent liver biopsy (due to any indication), participated in this study.

RESULTS

Liver biopsies were obtained from 210 patients. Seven of 210 cases were excluded due to unreliable data. A total of 209 liver biopsies were done in the rest of the cases (n=203). Of all cases of liver biopsies, 22 (10.5%) experienced complications after biopsy. Pain (n=7) was the most frequent complication in 22 cases of liver biopsy. Mortality rate was one (0.5%) due to rupture of subcapsular haematoma. In terms of complication (p=0.592), there was no significant difference statistically between patients with blind liver biopsy (n=16) and patients with ultrasound-guided liver biopsy (n=6).

CONCLUSION

In terms of complications, there was no significant difference when the patients were evaluated with and without ultrasound-guided biopsy.

摘要

背景与研究目的

肝活检是肝病诊断及随访中一项成熟的检查方法。肝活检的并发症虽罕见但可能致命。本研究旨在评估经皮肝活检的并发症,并比较伊朗南部设拉子内马齐医院儿科病房中盲目及超声引导下经皮肝活检的并发症。

患者与方法

为完成调查问卷,回顾性分析了2008年至2012年间儿科患者因不同病因进行肝活检的登记信息。所有年龄在0至18岁、接受肝活检(因任何指征)的儿童均参与本研究。

结果

共获取210例患者的肝活检样本。210例中有7例因数据不可靠被排除。其余病例(n = 203)共进行了209次肝活检。在所有肝活检病例中,22例(10.5%)在活检后出现并发症。疼痛(n = 7)是22例肝活检中最常见的并发症。因包膜下血肿破裂导致的死亡率为1例(0.5%)。在并发症方面(p = 0.592),盲目肝活检患者(n = 16)与超声引导下肝活检患者(n = 6)之间无统计学显著差异。

结论

在并发症方面,超声引导活检与未采用超声引导活检的患者评估结果无显著差异。

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