Johns Emily, Tracey Irene
Clinical Fellow in Gastroenterology, Centre for Functional Magnetic Resonance Imaging of the Brain John Radcliffe Hospital Oxford, OX3 9DU.
Professor of Anaesthetic Science, Centre for Functional Magnetic Resonance Imaging of the Brain John Radcliffe Hospital Oxford, OX3 9DU.
Rev Pain. 2009 Oct;3(2):2-5. doi: 10.1177/204946370900300202.
Functional neuroimaging allows conscious reporting by human subjects to be related to changes in brain activation during painful stimulation.Brain regions thought to be involved in the perception of pain include the primary and secondary somatosensory cortex, the anterior cingulate cortex, the prefrontal cortex, the insula and the thalamus.There are major similarities in how visceral pain and somatic pain are processed by the brain.No single brain region has been found to be responsible for visceral pain.Patients with IBS often activate the same brain regions as healthy controls in response to pain, but with differing intensities.Functional neuroimaging studies have failed to reach a consensus opinion on how the brain processes pain in Irritable Bowel Syndrome.
功能神经影像学能够将人类受试者的意识报告与疼痛刺激期间大脑激活的变化联系起来。被认为参与疼痛感知的脑区包括初级和次级躯体感觉皮层、前扣带回皮层、前额叶皮层、脑岛和丘脑。大脑处理内脏痛和躯体痛的方式存在主要相似之处。尚未发现单一脑区负责内脏痛。肠易激综合征患者在疼痛反应中通常激活与健康对照相同的脑区，但激活强度不同。功能神经影像学研究未能就大脑如何处理肠易激综合征中的疼痛达成共识。
