Kiu Kwong-Han, Hanizasurana Hashim, Zunaina Embong
Department of Ophthalmology, Hospital Selayang, Selayang, Selangor, Malaysia ; Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Department of Ophthalmology, Hospital Selayang, Selayang, Selangor, Malaysia.
Int Med Case Rep J. 2015 Oct 19;8:255-8. doi: 10.2147/IMCRJ.S91323. eCollection 2015.
A 22-year-old Malay female presented with left eye floaters for 2 weeks, associated with temporal visual field defect and metamorphopsia for 3 days. She has a guinea pig and a hedgehog at home, but denied being bitten or scratched by them. Her visual acuity at presentation was 6/12 on the left eye and 6/6 on the right eye. Her left eye relative afferent pupillary defect was barely positive with mild anterior chamber reaction. Fundus examination of the left eye showed mild vitritis, swollen optic disc with macular star, crops of active choroidal lesions at superonasal retina with a linear arrangement in the form of migratory track nasally. However, there were no nematodes seen on fundus examination. Investigations showed normal full blood count with no eosinophilia and positive serology test for Bartonella henselae. She was diagnosed to have dual infection - diffuse unilateral subacute neuroretinitis (DUSN), based on the presence of crops of choroidal lesions with migratory track, and cat scratch disease (CSD) based on a positive serological test. She was treated with oral albendazole 400 mg 12 hourly for 6 weeks for DUSN and oral doxycycline 100 mg 12 hourly for 4 weeks for CSD. Focal laser had been applied to the area of migratory track in the left eye. Her left eye vision improved to 6/6 at 1 month after treatment, with resolution of neuroretinitis.
一名22岁的马来女性因左眼飞蚊症2周就诊,伴有颞侧视野缺损和视物变形3天。她家中养了一只豚鼠和一只刺猬,但否认被它们咬伤或抓伤。就诊时她的左眼视力为6/12,右眼视力为6/6。她的左眼相对传入性瞳孔障碍仅为弱阳性,伴有轻度前房反应。左眼眼底检查显示轻度玻璃体炎,视盘肿胀伴黄斑星芒,视网膜鼻上象限有散在的活动性脉络膜病变,呈向鼻侧迁移的线性排列。然而,眼底检查未见线虫。检查显示全血细胞计数正常,无嗜酸性粒细胞增多,汉赛巴尔通体血清学检测呈阳性。基于存在呈迁移轨迹的脉络膜病变,她被诊断为双重感染——弥漫性单侧亚急性神经视网膜炎(DUSN),基于血清学检测呈阳性,诊断为猫抓病(CSD)。她因DUSN接受口服阿苯达唑400毫克,每12小时一次,共6周的治疗,因CSD接受口服强力霉素100毫克,每12小时一次,共4周的治疗。已对左眼迁移轨迹区域进行了局部激光治疗。治疗1个月后,她的左眼视力提高到6/6,神经视网膜炎消退。