小儿亨氏巴尔通体性视神经视网膜炎掩盖合并感染
Pediatric Bartonella henselae neuroretinitis masking co-infections.
作者信息
Pham Gina, Dermarkarian Christopher R, Tran Jeffrey, Shah Veeral S
机构信息
Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, USA.
Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin Street, Houston, TX, USA.
出版信息
Am J Ophthalmol Case Rep. 2022 Jan 20;25:101272. doi: 10.1016/j.ajoc.2022.101272. eCollection 2022 Mar.
PURPOSE
Neuroretinitis (NR) is an inflammatory disorder that presents with painless vision loss due to optic disc edema, peripapillary detachment, and macular lipid exudation. We report the first two documented cases of co-infections of pediatric NR due to Bartonella henselae with HSV and Toxocara cati, respectively.
OBSERVATIONS
A 10-year-old female with acute right-sided facial droop, right eye pain, and acute visual loss of the right eye is diagnosed with co-infection of Bartonella and HSV retinitis and is successfully treated with acyclovir, rifampin, and doxycycline. A 13-year-old female with progressive visual loss of the left eye is diagnosed with co-infection of Bartonella and ocular toxocariasis and is successfully treated with doxycycline, rifampin, prednisolone, and albendazole.
CONCLUSIONS AND IMPORTANCE
Early recognition and multi-modal treatment is necessary to prevent delayed diagnosis and treat the underlying NR causes for optimal visual recovery.
目的
视神经视网膜炎（NR）是一种炎症性疾病，因视盘水肿、视乳头周围脱离和黄斑脂质渗出而出现无痛性视力丧失。我们报告了首例分别由亨氏巴尔通体与单纯疱疹病毒（HSV）和猫弓首线虫共同感染导致小儿NR的两个病例记录。
观察结果
一名10岁女性，出现急性右侧面部下垂、右眼疼痛和右眼急性视力丧失，被诊断为巴尔通体与HSV视网膜炎共同感染，并成功接受了阿昔洛韦、利福平及强力霉素治疗。一名13岁女性，左眼进行性视力丧失，被诊断为巴尔通体与眼弓蛔虫病共同感染，并成功接受了强力霉素、利福平、泼尼松龙及阿苯达唑治疗。
结论与意义
早期识别和多模式治疗对于预防延迟诊断及治疗潜在的NR病因以实现最佳视力恢复是必要的。
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