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评估牙龈黏附性疏水氯己定凝胶治疗慢性牙周炎的短期效果

Short-Term Results in Evaluating a Gingiva-Adhesive Hydrophobic-Chlorhexidine-Gel for Chronic Periodontitis.

作者信息

Sarbu Ciprian, Rusu Darian, Călniceanu Horia, Kasaj Adrian, Petrutiu Stefan Adrian, Roman Alexandra, Soancă Andrada, PicoȘ Alina, Stratul Stefan Ioan, Jentsch Holger

机构信息

Department of Periodontology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

Department of Dental Medicine, Faculty Of Medicine and Pharmacy, Oradea University, Romania.

出版信息

Clujul Med. 2014;87(3):186-91. doi: 10.15386/cjmed-312. Epub 2014 Aug 5.

Abstract

BACKGROUND AND AIMS

Oral mucosa and interproximal spaces of the teeth could favor the colonization of periodontopathogenic bacteria, which could be targeted by chemical antiplaque agents such as chlorhexidine, present in different oral hygiene products, thus improving the control of biofilm growth and delaying microbial accumulation. The study aimed to evaluate whether the use of a hydrophobic gel with good gingival adhesion for 14 days after the scaling and root planing of patients with chronic periodontitis would improve the treatment outcome, when compared with the use of a regular hydrophyllic gel.

MATERIAL AND METHODS

Patients with moderate disease were included in two study groups. At baseline and 3 months after the treatment the following parameters were recorded: pocket depth, Approximal Plaque Index, Modified Gingival Index, Simplified Oral Hygiene Index, bleeding on probing. Patients received scaling and root planing in two sessions at 24 hours interval. After the treatment, patients in the test group applied the hydrophobic adhesive chlorhexidine gel once a day, every other day, while in the control group the gel was used twice daily.

RESULTS

Both treatments resulted in significant improvement in all clinical indices, except Approximal Plaque Index, which deteriorated significantly in both groups. Three months after mechanical treatment, the mean probing depth changed in the test group from 4.16±0.45 mm to 2.80±0.42 mm, and in the control group from 4.16±0.30 to 2.69±0.19.

CONCLUSIONS

Both adjunctive anti-infective therapies induced clinical improvement 3 months from baseline. The differences between the two treatments were not statistically significant.

摘要

背景与目的

口腔黏膜和牙齿邻间隙有利于牙周病原菌的定植,而不同口腔卫生产品中含有的洗必泰等化学防菌斑剂可针对这些病原菌,从而改善生物膜生长的控制并延缓微生物积聚。本研究旨在评估,对于慢性牙周炎患者,在龈下刮治和根面平整术后使用具有良好牙龈黏附性的疏水凝胶14天,与使用常规亲水凝胶相比,是否能改善治疗效果。

材料与方法

将中度病情患者纳入两个研究组。在基线和治疗后3个月记录以下参数:牙周袋深度、邻面菌斑指数、改良牙龈指数、简化口腔卫生指数、探诊出血。患者分两次进行龈下刮治和根面平整,间隔24小时。治疗后,试验组患者每隔一天每天使用一次疏水黏附性洗必泰凝胶,而对照组患者每天使用两次该凝胶。

结果

两种治疗方法均使所有临床指标有显著改善,但邻面菌斑指数除外,两组该指标均显著恶化。机械治疗3个月后,试验组平均探诊深度从4.16±0.45毫米变为2.80±0.42毫米,对照组从4.16±0.30变为2.69±0.19。

结论

两种辅助抗感染治疗均使自基线起3个月的临床状况得到改善。两种治疗方法之间的差异无统计学意义。

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