Kondreddy Kameswari, Ambalavanan N, Ramakrishna T, Kumar R Saravana
Department of Periodontology and Imlantology, Meenakshi Ammal Dental College, Maduravoyal, Chennai, India.
J Indian Soc Periodontol. 2012 Oct;16(4):553-7. doi: 10.4103/0972-124X.106909.
The aim of this study is to evaluate the effectiveness of a controlled-release chlorhexidine chip as an adjunctive therapy to scaling and root planing when compared with scaling and root planing alone in the treatment of chronic periodontitis.
20 patients with a total number of 40 posterior sites were selected. These sites were divided into two groups in a split mouth design,: Group A (control site) had 20 sites treated with scaling and root planing alone and Group B (test site) had 20 sites treated with scaling and root planing and PerioCol™-CG. The clinical parameters (Plaque index, bleeding on probing, probing pocket depth, clinical attachment level) were recorded at baseline, 90(th) and 180(th) day for both the groups.
When both groups were compared the change in Plaque index was significantly higher in Group B when compared to Group A on the 90(th) day and 180(th) day. However, there was no statistically significant difference in the mean percentage of gingival bleeding sites between the two groups on the 90(th) day, though Group B showed a statistically higher reduction in the mean percentage of gingival bleeding sites at the end of 180(th) day. There was no statistically significant difference in probing pocket depth between the two groups on both 90(th) and 180(th) day. Gain in clinical attachment level was significantly higher in Group B when compared to Group A on the 90(th) and 180(th) day.
From the results observed in this study, it can be concluded that the adjunctive use of PerioCol™-CG was safe and provided significant improvement in both Plaque index and gingival bleeding index. It was also more favorable than scaling and root planing alone for gain in clinical attachment level.
本研究的目的是评估与单纯龈下刮治和根面平整相比，缓释洗必泰芯片作为辅助治疗慢性牙周炎时的有效性。
选取20例患者共40个后牙部位。这些部位采用分口设计分为两组：A组（对照部位）20个部位仅接受龈下刮治和根面平整，B组（试验部位）20个部位接受龈下刮治、根面平整及PerioCol™-CG治疗。记录两组在基线、第90天和第180天时的临床参数（菌斑指数、探诊出血、探诊袋深度、临床附着水平）。
两组比较时，第90天和第180天时B组菌斑指数的变化显著高于A组。然而，第90天时两组间牙龈出血部位的平均百分比无统计学显著差异，尽管B组在第180天时牙龈出血部位的平均百分比有统计学意义上的更高降幅。第90天和第180天时两组间探诊袋深度均无统计学显著差异。第90天和第180天时B组临床附着水平的增加显著高于A组。
从本研究观察到的结果可以得出结论，辅助使用PerioCol™-CG是安全的，并且在菌斑指数和牙龈出血指数方面均有显著改善。在临床附着水平增加方面，它也比单纯龈下刮治和根面平整更有利。
