Sowa Nathaniel A, Cholera Rushina, Pence Brian W, Gaynes Bradley N
101 Manning Drive, Campus Box 7160, Chapel Hill, NC 27514
J Clin Psychiatry. 2015 Oct;76(10):1385-96. doi: 10.4088/JCP.14r09186.
To systematically review the literature on prevalence and incidence of perinatal depression in human immunodeficiency virus (HIV)-infected African women.
We searched 17 databases, including PubMed, PsycINFO, Cochrane, EMBASE, Web of Science, ClinicalTrials.gov, Google Scholar, and OpenGrey, from inception through August 2014 using the search strategy ((antenatal OR peripartum OR perinatal OR postnatal OR postpartum) AND (depression OR mental disorder) AND HIV AND Africa NOT (-) American).
We included English-language articles on studies conducted in Africa with prevalence or incidence rates of diagnostically confirmed depression or suspected depression in HIV-infected women during pregnancy through 12 months postpartum.
We examined details of study design, location, means of measurement, incidence and prevalence rates of diagnostically confirmed depression or suspected depression and any associated risk factors for development of depression. Mean prevalence rates were calculated and weighted based on study size.
Twenty-two articles met inclusion criteria. Two reported diagnostically confirmed antenatal depression, and 9 reported suspected antenatal depression prevalence. Two reported diagnostically confirmed postnatal depression, and 10 reported suspected postnatal depression prevalence. Weighted mean prevalence of antenatal depression was 23.4%, and suspected antenatal depression was 43.5%. Weighted mean prevalence of postnatal depression was 22.5%, and suspected postnatal depression was 31.1%. No studies reported incidence rates.
Few studies have examined the rate of perinatal depression in HIV-infected African women. Existing studies show a high prevalence of perinatal depression, with even higher prevalence rates of suspected depression. No data on the incidence of perinatal depression in this population exist.
系统回顾关于感染人类免疫缺陷病毒（HIV）的非洲女性围产期抑郁症患病率和发病率的文献。
我们检索了17个数据库，包括PubMed、PsycINFO、Cochrane、EMBASE、科学网、ClinicalTrials.gov、谷歌学术和OpenGrey，检索时间从各数据库建库起至2014年8月，检索策略为（（产前或围产期或产后或产后）且（抑郁症或精神障碍）且HIV且非洲 非（-）美洲）。
我们纳入了在非洲开展的英文研究，这些研究涉及孕期至产后12个月期间HIV感染女性经诊断确认的抑郁症或疑似抑郁症的患病率或发病率。
我们研究了研究设计、地点、测量方法、经诊断确认的抑郁症或疑似抑郁症的发病率和患病率以及任何与抑郁症发生相关的危险因素的详细信息。计算平均患病率并根据研究规模进行加权。
22篇文章符合纳入标准。2篇报告了经诊断确认的产前抑郁症，9篇报告了疑似产前抑郁症患病率。2篇报告了经诊断确认的产后抑郁症，10篇报告了疑似产后抑郁症患病率。产前抑郁症的加权平均患病率为23.4%，疑似产前抑郁症为43.5%。产后抑郁症的加权平均患病率为22.5%，疑似产后抑郁症为31.1%。没有研究报告发病率。
很少有研究调查感染HIV的非洲女性围产期抑郁症的发生率。现有研究表明围产期抑郁症患病率很高，疑似抑郁症的患病率更高。该人群中围产期抑郁症发病率尚无数据。
