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[银杏叶提取物肠外治疗中的微循环]

[Microcirculation in parenteral Ginkgo biloba extract therapy].

作者信息

Költringer P, Eber O, Klima G, Rothlauer W, Wakonig P, Langsteger W, Lind P

机构信息

Krankenhaus der Barmherzigen Brüder, Graz-Eggenberg.

出版信息

Wien Klin Wochenschr. 1989 Mar 17;101(6):198-200.

PMID:2652887
Abstract

15 patients with arteriosclerotic lesions in the extracranial brain arteries, randomly selected, were treated with an infusion of 250 ml physiological NaCl and 25 ml Ginkgo biloba extract (Tebonin). A second group (n = 15) received 250 ml NaCl without drugs stimulating blood flow. The skin microcirculation was measured in vivo by means of a helium-neon laser at one of the 4 extremities. Perfusion increased significantly (p less than or equal to 0.01) in response to Ginkgo biloba extract als composed with the response in the control group. The results justify the administration of Ginkgo biloba extract in vascular diseases.

摘要

随机选取15例颅外脑动脉有动脉硬化病变的患者,给予输注250毫升生理氯化钠溶液和25毫升银杏叶提取物(金纳多)进行治疗。第二组(n = 15)接受250毫升不含促进血流药物的氯化钠溶液。通过氦氖激光在四肢之一对皮肤微循环进行活体测量。与对照组相比,银杏叶提取物使灌注显著增加(p≤0.01)。这些结果证明了银杏叶提取物在血管疾病中的应用价值。

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1
[Microcirculation in parenteral Ginkgo biloba extract therapy].[银杏叶提取物肠外治疗中的微循环]
Wien Klin Wochenschr. 1989 Mar 17;101(6):198-200.
2
[Collagen-induced thrombocyte aggregation in parenteral therapy using Ginkgo biloba].[银杏叶在肠外治疗中诱导的血小板聚集]
Wien Med Wochenschr. 1989 Mar 15;139(5):92-4.
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The effect of intravenous infusion of Tebonin (Ginkgo biloba) on pial arteries in cats.静脉输注金纳多(银杏叶提取物)对猫软脑膜动脉的影响。
J Neurosurg Sci. 1983 Oct-Dec;27(4):227-31.
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Effects of Ginkgo biloba extract on cerebral oxygen and glucose metabolism in elderly patients with pre-existing cerebral ischemia.银杏叶提取物对已有脑缺血的老年患者脑氧和葡萄糖代谢的影响。
Complement Ther Med. 2015 Apr;23(2):220-5. doi: 10.1016/j.ctim.2014.12.009. Epub 2015 Jan 5.
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A new ginkgo fresh plant extract increases microcirculation and radical scavenging activity in elderly patients.一种新型银杏新鲜植物提取物可增加老年患者的微循环和自由基清除活性。
Adv Ther. 2011 Dec;28(12):1078-88. doi: 10.1007/s12325-011-0083-4. Epub 2011 Nov 24.
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[Hemorheologic effects of ginkgo biloba extract EGb 761. Dose-dependent effect of EGb 761 on microcirculation and viscoelasticity of blood].[银杏叶提取物EGb 761的血液流变学效应。EGb 761对微循环和血液粘弹性的剂量依赖性效应]
Fortschr Med. 1993 Apr 10;111(10):170-2.
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The therapeutic effect of Ginkgo biloba extract in SHR rats and its possible mechanisms based on cerebral microvascular flow and vasomotion.银杏叶提取物对自发性高血压大鼠的治疗作用及其基于脑微血管血流和血管运动的可能机制。
Clin Hemorheol Microcirc. 2000;23(2-4):133-8.
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[Disorders of brain performance of vascular origin. Randomized double-blind study of the effectiveness of Gingko biloba extract].[血管源性脑功能障碍。银杏叶提取物有效性的随机双盲研究]
Fortschr Med. 1988 Jun 30;106(19):408-12.
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Effects of extract of Ginkgo biloba on spasms of the basilar artery and cerebral microcirculatory perfusion in rats with subarachnoid hemorrhage.银杏叶提取物对蛛网膜下腔出血大鼠基底动脉痉挛和脑微循环灌注的影响。
Clin Hemorheol Microcirc. 2003;29(3-4):231-8.
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Comparison of two dosages of ginkgo biloba extract EGb 761 in patients with peripheral arterial occlusive disease Fontaine's stage IIb. A randomised, double-blind, multicentric clinical trial.两种剂量银杏叶提取物EGb 761用于外周动脉闭塞性疾病Fontaine IIb期患者的比较:一项随机、双盲、多中心临床试验。
Arzneimittelforschung. 1999 Nov;49(11):900-4. doi: 10.1055/s-0031-1300524.

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