Iliff L D, Auer L M
J Neurosurg Sci. 1983 Oct-Dec;27(4):227-31.
The dilatory effect of intravenously infused Tebonin (extract of Ginkgo biloba) on pial arterial vessels (less than 100 micron diameter), has been measured using a multichannel videoangiometer through a closed cranial window in cats. After 20 minutes there was a significant dilatation of 7% which increased to 21% by one hour. Results from 6 cats treated with 0.3 mg/kg/min. Tebonin were compared with a group of 6 control cats; the same blood gas "steady state" situation applying to both groups. Results imply a cerebral metabolic effect of Ginkgo biloba that induced a slow rise in cerebral blood flow.
通过猫的闭合颅骨窗口，使用多通道视频血管造影仪测量了静脉输注金纳多（银杏叶提取物）对软脑膜动脉血管（直径小于100微米）的扩张作用。20分钟后出现了7%的显著扩张，到1小时时增加到21%。对6只以0.3毫克/千克/分钟的剂量接受金纳多治疗的猫的结果，与一组6只对照猫的结果进行了比较；两组的血气“稳态”情况相同。结果表明银杏叶具有脑代谢效应，可导致脑血流量缓慢增加。
