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[肾移植术后早期的感染性并发症]

[Infectious complications in the early phase following kidney transplantation].

作者信息

Spielberger M, Schmid T, Sandbichler P, Pernthaler H, Bösmüller C, Semenitz E, Margreiter R

机构信息

Abteilung für Transplantationschirurgie, I. Universitätsklinik für Chirurgie, Innsbruck.

出版信息

Wien Klin Wochenschr. 1989 Mar 31;101(7):238-41.

PMID:2652893
Abstract

A retrospective analysis of 533 patients receiving kidney transplantation was performed to study the incidence of infection in the early postoperative period. Mostly localized in the lungs and renal system, bacterial complications arose in 133 patients. As compared with the unproblematic management of the urinary tract infections, 45 pulmonary infections were characterized by difficulties in diagnosis and treatment. Poor graft function was closely related to pulmonary infections: mean creatinine was 2.4 mg% (in patients without pneumonia - 1.5 mg%). Out of 45 patients with pneumonia, the graft failed in 16 patients. 6 patients died as a result of pneumonia. Rapid detection of the pathogenic organism is required, if necessary by invasive diagnosis. The administration of erythromycin before identification of the responsible pathogen may be indicated, in view of the fatal outcome in several patients subsequently diagnosed as having Legionella infection.

摘要

对533例接受肾移植的患者进行了回顾性分析,以研究术后早期感染的发生率。细菌并发症主要发生在133例患者中,多局限于肺部和泌尿系统。与尿路感染的顺利处理相比,45例肺部感染的诊断和治疗存在困难。移植肾功能差与肺部感染密切相关:平均肌酐为2.4mg%(无肺炎患者为1.5mg%)。45例肺炎患者中,16例移植失败。6例患者死于肺炎。如有必要,需要通过侵入性诊断快速检测致病微生物。鉴于一些随后被诊断为军团菌感染的患者出现了致命后果,在确定病原体之前可考虑使用红霉素。

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