Momeni Maryam, Ghanbari Atefeh, Bidabadi Elham, Yousefzadeh-Chabok Shahrokh
Maryam Momeni, MSc, is Instructor, Qazvin Nursing and Midwifery College, Qazvin University of Medical Sciences, Qazvin, Iran. Questions or comments about this article may be directed to Atefeh Ghanbari, PhD, at
J Neurosci Nurs. 2015 Dec;47(6):340-5. doi: 10.1097/JNN.0000000000000173.
The effects of epilepsy may disturb the ability of the child and family to function and has detrimental effects on health-related quality of life (HRQOL). We determined HRQOL and related factors in children and adolescents with epilepsy in Iran. This cross-sectional study was performed in a private neurology pediatric clinic in Guilan Province (North of Iran). We evaluated 108 children and adolescents with epilepsy. Data were collected by interview with parents and review of medical records. Generic and specific HRQOL was evaluated by Child Health Questionnaire and QOL in Childhood Epilepsy Questionnaire, respectively. The mean of overall generic HRQOL score was 71.05 ± 11.31. The lowest score was related to parental impact: emotional (52.59 ± 15.49). The average total specific HRQOL score was 71.95 ± 11.16. The lowest score dedicated to general health (51.21 ± 18.25). In multivariate regression analysis, duration of epilepsy (p < .016) was independently associated with generic HRQOL scores. Variables were independently associated with specific HRQOL scores including gender (p < .003), duration of epilepsy (p < .011), and family history of epilepsy (p < .005). We found that epilepsy duration was the strongest predictor of both generic and specific HRQOL in children and adolescents with epilepsy. This will be useful for clinicians in epilepsy management, which will enhance HRQOL.
癫痫的影响可能会干扰儿童及其家庭的正常功能，并对健康相关生活质量（HRQOL）产生不利影响。我们确定了伊朗癫痫儿童和青少年的健康相关生活质量及其相关因素。这项横断面研究在吉兰省（伊朗北部）的一家私立儿科神经科诊所进行。我们评估了108名癫痫儿童和青少年。通过与家长访谈和查阅病历收集数据。分别采用儿童健康问卷和儿童癫痫生活质量问卷评估一般和特定的健康相关生活质量。一般健康相关生活质量总分的平均值为71.05±11.31。得分最低的是父母的影响：情绪方面（52.59±15.49）。特定健康相关生活质量总得分的平均值为71.95±11.16。得分最低的是总体健康状况（51.21±18.25）。在多变量回归分析中，癫痫病程（p<.016）与一般健康相关生活质量得分独立相关。与特定健康相关生活质量得分独立相关的变量包括性别（p<.003）、癫痫病程（p<.011）和癫痫家族史（p<.005）。我们发现癫痫病程是癫痫儿童和青少年一般及特定健康相关生活质量的最强预测因素。这对癫痫管理中的临床医生很有用，有助于提高健康相关生活质量。
