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[骨密度测量]

[Bone mineral density measurement].

作者信息

Ito Masako

出版信息

Nihon Rinsho. 2015 Oct;73(10):1659-63.

PMID:26529927
Abstract

Bone mineral density (BMD) is measured using X-ray or γ-ray, and dual energy X-ray absorptiometry (DXA) using X-ray beam is a standard method for the osteoporosis diagnosis and monitoring. Quantitative computed tomography (QCT) provides volumetric BMD as well as geometric information based on the three-dimensional CT image data, which contributes to evaluate the pathophysiology and efficacy of anti-osteoporotic agents. High resolution peripheral QCT becomes widespread, which provides volumetric BMD as well as microstructural parameters in the radius and tibia. This is the only modality to assess microstructure in the spongiosa and cortices with high resolution in vivo.

摘要

骨密度(BMD)通过X射线或γ射线进行测量,使用X射线束的双能X线吸收法(DXA)是骨质疏松症诊断和监测的标准方法。定量计算机断层扫描(QCT)基于三维CT图像数据提供体积骨密度以及几何信息,这有助于评估抗骨质疏松药物的病理生理学和疗效。高分辨率外周QCT得到广泛应用,它可提供桡骨和胫骨的体积骨密度以及微观结构参数。这是唯一一种能够在体内以高分辨率评估松质骨和皮质骨微观结构的方法。

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