Bisphosphonates (BPs) are first-line drugs in the management of osteoporosis. BPs' significant efficacy in the prevention of vertebral, non-vertebral, and hip fractures has been proven. BPs are now available as an injection as well as as oral administration in Japan. This review gives an overview of the efficacy as well as the clinical issues of the bisphosphonates.
双膦酸盐类药物（BPs）是骨质疏松症治疗的一线药物。双膦酸盐类药物在预防椎体、非椎体和髋部骨折方面的显著疗效已得到证实。在日本，双膦酸盐类药物现在既有注射剂型，也有口服剂型。本综述概述了双膦酸盐类药物的疗效以及临床问题。
