Concha L Luciana, Durruty A Pilar, García de Los Ríos A Manuel
Rev Med Chil. 2015 Sep;143(9):1215-8. doi: 10.4067/S0034-98872015000900017.
Ketosis prone type 2 diabetes (KPD) is presently a well-defined clinical entity, characterized by a debut with severe hyperglycemia and ketoacidosis similar to the presenting form of Type 1 diabetes mellitus (DM1). However, it appears in subjects with Type 2 diabetes mellitus (DM2) phenotype. This situation is caused by an acute, reversible dysfunction of the beta cell in individuals with insulin resistance. Once the acute stage subsides, patients behave as having a DM2 and do not require insulin treatment. They should be kept on a diet and oral hypoglycemic drugs due to their susceptibility to have recurrent acute ketotic decompensations.
酮症倾向2型糖尿病（KPD）目前是一种明确的临床实体，其特征是起病时伴有严重高血糖和酮症酸中毒，类似于1型糖尿病（DM1）的表现形式。然而，它出现在具有2型糖尿病（DM2）表型的个体中。这种情况是由胰岛素抵抗个体的β细胞急性、可逆性功能障碍引起的。一旦急性期消退，患者表现为患有DM2，且不需要胰岛素治疗。由于他们易发生反复急性酮症失代偿，应坚持饮食控制并使用口服降糖药。
