急性期易发生酮症的非典型糖尿病与促炎状态相关：撒哈拉以南非洲人群的病例对照研究 - Suppr

Acute phase ketosis-prone atypical diabetes is associated with a pro-inflammatory profile: a case-control study in a sub-Saharan African population.

作者信息

Lontchi-Yimagou Eric, Boudou Philippe, Nguewa Jean Louis, Noubiap Jean Jacques, Kamwa Vicky, Djahmeni Eric Noel, Atogho-Tiedeu Babara, Azabji-Kenfack Marcel, Etoa Martine, Lemdjo Gaelle, Dehayem Mesmin Yefou, Mbanya Jean Claude, Gautier Jean-Francois, Sobngwi Eugène

机构信息

1Laboratory for Molecular Medicine and Metabolism, Biotechnology Center, University of Yaoundé 1, PO Box 87, Yaoundé, Cameroon.

2Unit of Hormonal Biology, Department of Biochemistry, Saint-Louis University Hospital, Assistance Publique-Hôpitaux de Paris (APHP), 1 avenue Claude Vellefaux, 75010 Paris, France.

出版信息

J Diabetes Metab Disord. 2018 Mar 29;17(1):37-43. doi: 10.1007/s40200-018-0336-8. eCollection 2018 Jun.

DOI:10.1007/s40200-018-0336-8

PMID:30288384

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6154517/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3120/6154517/f457ccd02c58/40200_2018_336_Fig1_HTML.jpg

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Acute phase ketosis-prone atypical diabetes is associated with a pro-inflammatory profile: a case-control study in a sub-Saharan African population.急性期易发生酮症的非典型糖尿病与促炎状态相关：撒哈拉以南非洲人群的病例对照研究

J Diabetes Metab Disord. 2018 Mar 29;17(1):37-43. doi: 10.1007/s40200-018-0336-8. eCollection 2018 Jun.

Ketosis-prone type 2 diabetes in patients of sub-Saharan African origin: clinical pathophysiology and natural history of beta-cell dysfunction and insulin resistance.撒哈拉以南非洲裔患者的酮症倾向2型糖尿病：β细胞功能障碍和胰岛素抵抗的临床病理生理学及自然史

Diabetes. 2004 Mar;53(3):645-53. doi: 10.2337/diabetes.53.3.645.

Diabetes in sub-Saharan Africa.撒哈拉以南非洲的糖尿病问题。

Lancet. 2010 Jun 26;375(9733):2254-66. doi: 10.1016/S0140-6736(10)60550-8.

Should diabetic ketosis without acidosis be included in ketosis-prone type 2 diabetes mellitus?糖尿病酮症而非酸中毒是否应纳入糖尿病酮症倾向 2 型糖尿病？

Diabetes Metab Res Rev. 2014 Jan;30(1):54-9. doi: 10.1002/dmrr.2448.

Diabetes in Africans. Part 2: Ketosis-prone atypical diabetes mellitus.非洲人的糖尿病。第2部分：易发生酮症的非典型糖尿病

Diabetes Metab. 2002 Feb;28(1):5-12.

Human herpesvirus 8 infection DNA positivity is associated with low insulin secretion: A case-control study in a sub-Saharan African population with diabetes.人类疱疹病毒 8 感染 DNA 阳性与胰岛素分泌不足有关：在撒哈拉以南非洲的糖尿病患者中的病例对照研究。

J Diabetes. 2018 Nov;10(11):866-873. doi: 10.1111/1753-0407.12777. Epub 2018 May 28.

A sub-Saharan African perspective of diabetes.撒哈拉以南非洲地区对糖尿病的看法。

Diabetologia. 2009 Jan;52(1):8-16. doi: 10.1007/s00125-008-1167-9. Epub 2008 Oct 10.

Ketosis-Prone Type 2 Diabetes: A Case Series.酮症倾向2型糖尿病：病例系列

Front Endocrinol (Lausanne). 2019 Oct 16;10:684. doi: 10.3389/fendo.2019.00684. eCollection 2019.

[Ketosis-prone type 2 diabetes mellitus in sub-Saharan Africans: possible contribution of human herpes virus 8 infection].[撒哈拉以南非洲人中的酮症倾向2型糖尿病：人疱疹病毒8感染的可能作用]

Med Sci (Paris). 2008 Jun-Jul;24(6-7):665-6. doi: 10.1051/medsci/20082467665.

[Study of acute inaugural ketosis-prone diabetes in a Hospital in Central-Eastern Tunisian].[突尼斯中东部某医院急性初发性酮症倾向糖尿病的研究]

Pan Afr Med J. 2018 Oct 23;31:134. doi: 10.11604/pamj.2018.31.134.12207. eCollection 2018.

引用本文的文献

Prevalence and clinical characteristics of hypertension and metabolic syndrome in newly diagnosed patients with ketosis-onset diabetes: a cross-sectional study.新诊断酮症起病糖尿病患者高血压和代谢综合征的患病率及临床特征：一项横断面研究

Diabetol Metab Syndr. 2019 Apr 25;11:31. doi: 10.1186/s13098-019-0426-x. eCollection 2019.

本文引用的文献

Ketosis-prone atypical diabetes in Cameroonian people with hyperglycaemic crisis: frequency, clinical and metabolic phenotypes.喀麦隆高血糖危象患者中易发生酮症的非典型糖尿病：发病率、临床和代谢表型

Diabet Med. 2017 Mar;34(3):426-431. doi: 10.1111/dme.13264. Epub 2016 Oct 15.

[Ketosis prone type 2 diabetes (KPD)].酮症倾向2型糖尿病（KPD）

Rev Med Chil. 2015 Sep;143(9):1215-8. doi: 10.4067/S0034-98872015000900017.

Association of HLA class II markers with autoantibody-negative ketosis-prone atypical diabetes compared to type 2 diabetes in a population of sub-Saharan African patients.在撒哈拉以南非洲患者群体中，与2型糖尿病相比，HLA II类标记物与自身抗体阴性的酮症倾向非典型糖尿病的关联。

Diabetes Res Clin Pract. 2015 Jan;107(1):31-6. doi: 10.1016/j.diabres.2014.10.002. Epub 2014 Nov 20.

Leukocyte profiles differ between type 1 and type 2 diabetes and are associated with metabolic phenotypes: results from the German Diabetes Study (GDS).白细胞谱在 1 型和 2 型糖尿病之间存在差异，并与代谢表型相关：来自德国糖尿病研究（GDS）的结果。

Diabetes Care. 2014 Aug;37(8):2326-33. doi: 10.2337/dc14-0316.

Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes.2型糖尿病中促炎细胞因子和胰岛驻留白细胞与胰岛功能障碍的关联

Diabetologia. 2014 Mar;57(3):491-501. doi: 10.1007/s00125-013-3116-5. Epub 2014 Jan 16.

Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes.胰岛特异性T细胞反应和促炎单核细胞定义了自身抗体阴性的酮症倾向糖尿病的亚型。

Diabetes Care. 2013 Dec;36(12):4098-103. doi: 10.2337/dc12-2328. Epub 2013 Oct 15.

Interaction between cytokines and inflammatory cells in islet dysfunction, insulin resistance and vascular disease.细胞因子与炎症细胞在胰岛功能障碍、胰岛素抵抗和血管疾病中的相互作用。

Diabetes Obes Metab. 2013 Sep;15 Suppl 3(0 3):117-29. doi: 10.1111/dom.12161.

STAT4 deficiency reduces obesity-induced insulin resistance and adipose tissue inflammation.STAT4 缺乏可减少肥胖引起的胰岛素抵抗和脂肪组织炎症。

Diabetes. 2013 Dec;62(12):4109-21. doi: 10.2337/db12-1275. Epub 2013 Aug 12.

Inflammatory biomarkers and progression of diabetic retinopathy in African Americans with type 1 diabetes.炎症生物标志物与非洲裔美国人 1 型糖尿病患者糖尿病视网膜病变的进展。

Invest Ophthalmol Vis Sci. 2013 Aug 13;54(8):5471-80. doi: 10.1167/iovs.13-12212.

Diabetes mellitus and inflammation.糖尿病与炎症。

Curr Diab Rep. 2013 Jun;13(3):435-44. doi: 10.1007/s11892-013-0375-y.

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Acute phase ketosis-prone atypical diabetes is associated with a pro-inflammatory profile: a case-control study in a sub-Saharan African population.

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