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使用单侧外固定器对软骨发育不全患者进行双侧肱骨延长术:是否安全且能否改善日常生活?

Bilateral humeral lengthening in achondroplasia with unilateral external fixators: is it safe and does it improve daily life?

作者信息

Balci H I, Kocaoglu M, Sen C, Eralp L, Batibay S G, Bilsel K

机构信息

Istanbul University Istanbul Medical Faculty, Capa/Fatih, 34690, Istanbul, Turkey.

Istanbul Memorial Hospital, Piyalepasa Bulvari Okmeydani 34385, Istanbul, Turkey.

出版信息

Bone Joint J. 2015 Nov;97-B(11):1577-81. doi: 10.1302/0301-620X.97B11.36037.

DOI:10.1302/0301-620X.97B11.36037
PMID:26530664
Abstract

A retrospective study was performed in 18 patients with achondroplasia, who underwent bilateral humeral lengthening between 2001 and 2013, using monorail external fixators. The mean age was ten years (six to 15) and the mean follow-up was 40 months (12 to 104). The mean disabilities of the arm, shoulder and hand (DASH) score fell from 32.3 (20 to 40) pre-operatively to 9.4 (6 to 14) post-operatively (p = 0.037). A mean lengthening of 60% (40% to 95%) was required to reach the goal of independent perineal hygiene. One patient developed early consolidation, and fractures occurred in the regenerate bone of four humeri in three patients. There were three transient radial nerve palsies. Humeral lengthening increases the independence of people with achondroplasia and is not just a cosmetic procedure.

摘要

对18例软骨发育不全患者进行了一项回顾性研究,这些患者在2001年至2013年间使用单轨外固定器进行了双侧肱骨延长术。平均年龄为10岁(6至15岁),平均随访时间为40个月(12至104个月)。手臂、肩部和手部功能障碍(DASH)评分的平均值从术前的32.3(20至40)降至术后的9.4(6至14)(p = 0.037)。为达到独立会阴卫生的目标,平均需要延长60%(40%至95%)。1例患者出现早期骨愈合,3例患者的4根肱骨再生骨发生骨折。出现3例短暂性桡神经麻痹。肱骨延长术提高了软骨发育不全患者的独立性,而不仅仅是一种美容手术。

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