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用于骨髓移植的白消安(Bu)和环磷酰胺(Cy)。

Busulfan (Bu) and cyclophosphamide (Cy) for marrow transplantation.

作者信息

Santos G W

机构信息

Johns Hopkins Oncology Center, Johns Hopkins University, Baltimore, Maryland.

出版信息

Bone Marrow Transplant. 1989 Jan;4 Suppl 1:236-9.

PMID:2653511
Abstract

Bu and Cy is a bone marrow transplant preparative regimen that is effective for ANLL and certain genetic diseases. It has shown promise in CML. Its effectiveness in ALL and lymphomas remains to be explored. The substitution of Bu for TBI in marrow transplant regimens would seem to have a number of practical and theoretical advantages.

摘要

白消安和环磷酰胺是一种对急性非淋巴细胞白血病(ANLL)和某些遗传性疾病有效的骨髓移植预处理方案。它在慢性粒细胞白血病(CML)中已显示出前景。其在急性淋巴细胞白血病(ALL)和淋巴瘤中的有效性仍有待探索。在骨髓移植方案中用白消安替代全身照射(TBI)似乎有许多实际和理论上的优势。

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