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分母有算数:用检测数据补充生殖器沙眼衣原体感染监测数据,2007 至 2013 年,挪威。

Denominators count: supplementing surveillance data for genital Chlamydia trachomatis infection with testing data, Norway, 2007 to 2013.

机构信息

Norwegian Institute of Public Health, Department of Infectious Disease Epidemiology, Oslo, Norway.

出版信息

Euro Surveill. 2015;20(36). doi: 10.2807/1560-7917.ES.2015.20.36.30012.

Abstract

As genital Chlamydia trachomatis (chlamydia) infection is often asymptomatic, surveillance of diagnosed cases is heavily influenced by the rate and distribution of testing. In 2007, we started supplementing case-based surveillance data from the Norwegian Surveillance System for Communicable Diseases (MSIS) with aggregated data on age group and sex of individuals tested. In this report, annual testing rates, diagnosis rates and proportion positive for chlamydia in Norway between 1990 and 2013 are presented. From 2007, rates are also stratified by age group and sex. The annual testing rate for chlamydia culminated in the early 1990s, with 8,035 tested per 100,000 population in 1991. It then declined to 5,312 per 100,000 in 2000 after which it remained relatively stable. Between 1990 and 2013 the annual rate of diagnosed cases increased 1.5 times from ca 300 to ca 450 per 100,000 population. The proportion of positive among the tested rose twofold from ca 4% in the 1990s to 8% in 2013. Data from 2007 to 2013 indicate that more women than men were tested (ratio: 2.56; 95% confidence interval (CI): 2.56-2.58) and diagnosed (1.54; 95% CI: 1.52-1.56). Among tested individuals above 14 years-old, the proportion positive was higher in men than women for all age groups. Too many tests are performed in women aged 30 years and older, where 49 of 50 tests are negative. Testing coverage is low (15%) among 15 to 24 year-old males. Information on sex and age-distribution among the tested helps to interpret surveillance data and provides indications on how to improve targeting of testing for chlamydia. Regular prevalence surveys may address remaining limitations of surveillance.

摘要

由于生殖器沙眼衣原体(衣原体)感染通常无症状,因此诊断病例的监测受到检测率和分布的严重影响。 2007 年,我们开始补充挪威传染病监测系统(MSIS)的基于病例的监测数据,增加了按年龄组和性别测试个体的汇总数据。在本报告中,介绍了 1990 年至 2013 年挪威衣原体的年度检测率,诊断率和阳性率。自 2007 年以来,这些比率还按年龄组和性别分层。衣原体的年度检测率在 90 年代初期达到顶峰,1991 年每 10 万人中有 8035 人接受了检测。然后,在 2000 年降至每 10 万人 5312 人,此后一直相对稳定。在 1990 年至 2013 年期间,每年诊断病例的发生率增加了 1.5 倍,从每 10 万人约 300 例增加到约 450 例。检测阳性的比例增加了两倍,从 90 年代的 4%增加到 2013 年的 8%。2007 年至 2013 年的数据表明,接受检测的女性多于男性(比例:2.56;95%置信区间(CI):2.56-2.58),诊断也更多(1.54;95%CI:1.52-1.56)。在 14 岁以上的受检者中,所有年龄组中男性的阳性比例均高于女性。在 30 岁及以上的女性中进行了过多的测试,其中 50 次测试中有 49 次为阴性。 15 至 24 岁男性的检测覆盖率(15%)较低。关于受检者的性别和年龄分布的信息有助于解释监测数据,并提供有关如何改善衣原体检测目标的指示。定期进行流行率调查可能会解决监测的剩余局限性。

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