Feldhoff C M, Reber T, Drachman R, Drukker A
Department of Pediatric Nephrology, University Hospitals, Essen, FRG.
Clin Nephrol. 1989 Apr;31(4):210-2.
A 16-year-old boy developed bullous lesions on fingers, ears, tongue, and buccal mucosa as well as cauliflower-like growths on the epiglottis and vocal cords 1 1/2 years after a second renal transplantation and exposure to sunlight while receiving cyclosporin A (CsA). Withdrawal of CsA was followed by complete resolution of skin and mucosal lesions. A predisposition for adverse reactions to CsA is suggested, as additional side effects of CsA therapy were also present.
一名16岁男孩在第二次肾移植并在接受环孢素A(CsA)治疗期间暴露于阳光下1年半后,手指、耳朵、舌头和颊黏膜出现大疱性病变,会厌和声带上出现菜花状赘生物。停用CsA后,皮肤和黏膜病变完全消退。由于CsA治疗还存在其他副作用,提示患者对CsA存在不良反应易感性。