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基因组学正在改变个人医疗保健和医学:个性化预防保健的曙光。

Genomics is changing personal healthcare and medicine: the dawn of iPH (individualized preventive healthcare).

作者信息

Mehrian-Shai Ruty, Reichardt Juergen K V

机构信息

Pediatric Hemato-Oncology, Chaim Sheba Medical Center, Ramat Gan, Israel.

Division of Tropical Health and Medicine, James Cook University, Townsville, QLD, Australia.

出版信息

Hum Genomics. 2015 Nov 4;9:29. doi: 10.1186/s40246-015-0052-0.

DOI:10.1186/s40246-015-0052-0
PMID:26537019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4634796/
Abstract

This opinion piece focuses on the convergence of information technology (IT) in the form of personal monitors, especially smart phones and possibly also smart watches, individual genomic information and preventive healthcare and medicine. This may benefit each one of us not only individually but also society as a whole through iPH (individualized preventive healthcare). This shift driven by genomic and other technologies may well also change the relationship between patient and physician by empowering the former but giving him/her also much more individual responsibility.

摘要

这篇观点文章聚焦于以个人监测设备形式存在的信息技术(IT)的融合,尤其是智能手机,也可能包括智能手表、个人基因组信息以及预防性医疗保健和医学。通过个性化预防性医疗保健(iPH),这不仅可能使我们每个人受益,也可能使整个社会受益。由基因组和其他技术推动的这种转变很可能也会改变患者与医生之间的关系,赋予前者权力,但同时也给予他/她更多的个人责任。

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本文引用的文献

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A new initiative on precision medicine.一项关于精准医学的新倡议。
N Engl J Med. 2015 Feb 26;372(9):793-5. doi: 10.1056/NEJMp1500523. Epub 2015 Jan 30.
2
From genetic counseling to "genomic counseling".从遗传咨询到“基因组咨询”。
Mol Genet Genomic Med. 2013 Nov;1(4):189-93. doi: 10.1002/mgg3.45.
3
Compositional and functional features of the gastrointestinal microbiome and their effects on human health.胃肠道微生物组的组成和功能特征及其对人类健康的影响。
Gastroenterology. 2014 May;146(6):1449-58. doi: 10.1053/j.gastro.2014.01.052. Epub 2014 Jan 29.
4
Time to rethink end-of-life care.是时候重新思考临终关怀了。
Med J Aust. 2011 Jun 6;194(11):563. doi: 10.5694/j.1326-5377.2011.tb03102.x.