Nam Y, Jung J, Park S S, Kim S J, Shin S J, Choi J H, Kim M, Yoon H E
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.
Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea.
Transpl Infect Dis. 2015 Dec;17(6):890-6. doi: 10.1111/tid.12452. Epub 2015 Nov 5.
We report the case of a renal transplant recipient with pulmonary and splenic mucormycosis whose demise was accelerated by a myocardial abscess. Once pulmonary and splenic mucormycosis was diagnosed, liposomal amphotericin B was started and immunosuppressant treatments were discontinued. The pulmonary cavities regressed during treatment, but new myocardial and peri-allograft abscesses developed. The myocardial abscess diffusely infiltrated the left ventricular wall and was associated with akinesia, which led to sudden cardiac arrest. This case demonstrates a rare manifestation of mucormycosis and highlights the fatality and invasiveness of this infection.
我们报告了一例肾移植受者发生肺和脾毛霉病的病例，其死亡因心肌脓肿而加速。一旦诊断出肺和脾毛霉病，即开始使用脂质体两性霉素B，并停止免疫抑制治疗。治疗期间肺空洞消退，但出现了新的心肌和移植周围脓肿。心肌脓肿弥漫性浸润左心室壁并伴有运动不能，导致心脏骤停。该病例显示了毛霉病的罕见表现，并突出了这种感染的致命性和侵袭性。
