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小儿局灶性房性心动过速的导管消融:使用现代标测系统的十年经验

Catheter Ablation of Pediatric Focal Atrial Tachycardia: Ten-Year Experience Using Modern Mapping Systems.

作者信息

Dieks Jana-K, Müller Matthias J, Schneider Heike E, Krause Ulrich, Steinmetz Michael, Paul Thomas, Kriebel Thomas

机构信息

Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University Göttingen, Robert-Koch Str. 40, 37075, Göttingen, Germany.

出版信息

Pediatr Cardiol. 2016 Mar;37(3):459-64. doi: 10.1007/s00246-015-1299-x. Epub 2015 Nov 4.

Abstract

Experience of catheter ablation of pediatric focal atrial tachycardia (FAT) is still limited. There are data which were gathered prior to the introduction of modern 3D mapping and navigation systems into the clinical routine. Accordingly, procedures were associated with significant fluoroscopy and low success rates. The aim of this study was to present clinical and electrophysiological details of catheter ablation of pediatric FAT using modern mapping systems. Since March 2003, 17 consecutive patients <20 years underwent electrophysiological study (EPS) for FAT using the NavX(®) system (n = 7), the non-contact mapping system (n = 6) or the LocaLisa(®) system (n = 4), respectively. Radiofrequency was the primary energy source; cryoablation was performed in selected patients with a focus close to the AV node. In 16 patients, a total number of 19 atrial foci (right-sided n = 13, left-sided n = 6) could be targeted. In the remaining patient, FAT was not present/inducible during EPS. On an intention-to-treat basis, acute success was achieved in 14/16 patients (87.5 %) with a median number of 11 (1-31) energy applications. Ablation was unsuccessful in two patients due to an epicardial location of a right atrial focus (n = 1) and a focus close to the His bundle (n = 1), respectively. Median procedure time was 210 (84-332) min, and median fluoroscopy time was 13.1 (4.5-22.5) min. In pediatric patients with FAT, 3D mapping and catheter ablation provided improved clinical quality of care. Catheter ablation may be considered early in the course of treatment of this tachyarrhythmia in symptomatic patients.

摘要

小儿局灶性房性心动过速(FAT)导管消融的经验仍然有限。有一些数据是在现代三维标测和导航系统引入临床常规之前收集的。因此,相关手术存在大量的透视曝光,且成功率较低。本研究的目的是介绍使用现代标测系统对小儿FAT进行导管消融的临床和电生理细节。自2003年3月以来,17例年龄<20岁的连续患者因FAT分别使用NavX®系统(n = 7)、非接触标测系统(n = 6)或LocaLisa®系统(n = 4)接受了电生理检查(EPS)。射频是主要能量源;在部分靠近房室结的病灶患者中进行了冷冻消融。16例患者共靶向了19个房性病灶(右侧n = 13,左侧n = 6)。在其余患者中,EPS期间未出现/诱发出FAT。在意向性治疗的基础上,14/16例患者(87.5%)获得急性成功,能量应用次数中位数为11次(1 - 31次)。两名患者消融失败,分别是由于右心房病灶位于心外膜(n = 1)和病灶靠近希氏束(n = 1)。手术时间中位数为210(84 - 332)分钟,透视时间中位数为13.1(4.5 - 22.5)分钟。对于小儿FAT患者,三维标测和导管消融提高了临床护理质量。对于有症状的患者,在这种快速心律失常的治疗过程中可早期考虑导管消融。

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