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使用特戊酸去氧皮质酮(DOCP)成功治疗一只患有原发性肾上腺皮质功能减退和严重低钠血症的猫。

Successful treatment of a cat with primary hypoadrenocorticism and severe hyponatremia with desoxycorticosterone pivalate (DOCP).

作者信息

Woolcock Andrew D, Ward Cynthia

机构信息

Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.

出版信息

Can Vet J. 2015 Nov;56(11):1158-60.

Abstract

A 6-year-old, castrated male Siamese cat was diagnosed with primary hypoadrenocorticism, confirmed by an adrenocorticotopic hormone (ACTH) stimulation test documenting both hypocortisolism and hypoaldosteronism. The cat was successfully treated using a combination of prednisolone and desoxycorticosterone pivalate (DOCP). This case demonstrates that DOCP can be used successfully as mineralocorticoid supplementation in cats with hypoadrenocorticism and may have a longer therapeutic duration than that in dogs.

摘要

一只6岁去势雄性暹罗猫被诊断为原发性肾上腺皮质功能减退,促肾上腺皮质激素(ACTH)刺激试验证实存在皮质醇减少症和醛固酮减少症。该猫使用泼尼松龙和特戊酸脱氧皮质酮(DOCP)联合治疗成功。本病例表明,DOCP可成功用于肾上腺皮质功能减退猫的盐皮质激素补充,且治疗持续时间可能比犬更长。

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