Smith Stephanie A, Freeman Lisa C, Bagladi-Swanson Mary
Department of Clinical Sciences College of Veterinary Medicine, Kansas State University, Manhattan 66506, USA.
J Am Anim Hosp Assoc. 2002 Jan-Feb;38(1):41-4. doi: 10.5326/0380041.
A 9-year-old, spayed female domestic shorthair cat presented for polyphagia, polydipsia, and polyuria following chronic methylprednisolone acetate therapy for pruritus. Initial diagnostics were consistent with uncomplicated diabetes mellitus. Serum calcium was within reference range. Within 12 hours the cat developed depression, anorexia, vomiting, and severe dehydration. Laboratory analysis indicated marked hypercalcemia as measured by both ionized and total calcium concentration. No underlying neoplastic or inflammatory process was identified. An adrenocorticotropic hormone stimulation test was indicative of adrenocortical insufficiency. The hypercalcemia resolved with glucocorticoid supplementation and correction of the dehydration. The diabetes mellitus and adrenal insufficiency both resolved within 9 weeks.
一只9岁已绝育的雌性家养短毛猫，因慢性醋酸甲基泼尼松龙治疗瘙痒后出现多食、多饮和多尿前来就诊。初步诊断符合单纯性糖尿病。血清钙在参考范围内。12小时内，这只猫出现抑郁、厌食、呕吐和严重脱水。实验室分析显示，通过离子钙和总钙浓度测量均表明有明显的高钙血症。未发现潜在的肿瘤或炎症过程。促肾上腺皮质激素刺激试验表明肾上腺皮质功能不全。补充糖皮质激素和纠正脱水后，高钙血症得到缓解。糖尿病和肾上腺功能不全在9周内均得到缓解。
