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静电纺丝作为一种用于生物医学应用的强大技术:一项精心挑选的综述。

Electrospinning as a powerful technique for biomedical applications: a critically selected survey.

作者信息

Villarreal-Gómez Luis Jesús, Cornejo-Bravo José Manuel, Vera-Graziano Ricardo, Grande Daniel

机构信息

a Escuela de Ciencias de Ingeniería y Tecnología , Universidad Autónoma de Baja California , Tijuana , Mexico.

b Facultad de Ciencias Químicas e Ingeniería , Universidad Autónoma de Baja California , Tijuana , Mexico.

出版信息

J Biomater Sci Polym Ed. 2016;27(2):157-76. doi: 10.1080/09205063.2015.1116885. Epub 2015 Dec 17.

Abstract

Nowadays, electrospinning has become one of the most versatile, easy, and cost-effective techniques to engineer advanced materials used for many applications, especially in the biomedical and environmental areas. Like the numerous patents around the world, the increasing number of papers witnesses the huge potential of this simple process, and many companies have been emerged during the last years to exploit its innumerable applications. This article presents a critically selected overview of polymers that can be used to produce nanofibers, along with the biomedical applications of the resulting electrospun scaffolds. We have focused on about seven natural and synthetic polymers, but many more can be found in the literature, either as their pristine state or as composites with ceramics, metals, and other polymers. The description of some strategies for nanofiber production, and the characterization used to evaluate their optimization, has been discussed. Finally, several polymers have been recognized as highlights for future work.

摘要

如今,静电纺丝已成为制造用于多种应用的先进材料的最通用、简便且经济高效的技术之一,尤其是在生物医学和环境领域。与世界各地众多的专利一样,论文数量的不断增加见证了这一简单工艺的巨大潜力,并且在过去几年中涌现出许多公司来开发其无数的应用。本文对可用于生产纳米纤维的聚合物进行了精心挑选的概述,并介绍了所得静电纺丝支架的生物医学应用。我们重点关注了约七种天然和合成聚合物,但文献中还能找到更多,它们既可以是原始状态,也可以是与陶瓷、金属和其他聚合物的复合材料。本文还讨论了纳米纤维生产的一些策略以及用于评估其优化的表征方法。最后,几种聚合物被认为是未来研究的重点。

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