新生儿重症监护病房中对危重型先天性心脏病进行脉搏血氧饱和度筛查。
Pulse oximetry screening for critical congenital heart disease in the neonatal intensive care unit.
作者信息
Goetz E M, Magnuson K M, Eickhoff J C, Porte M A, Hokanson J S
机构信息
Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
出版信息
J Perinatol. 2016 Jan;36(1):52-6. doi: 10.1038/jp.2015.150. Epub 2015 Nov 5.
OBJECTIVE
Pulse oximetry screening (POS) is an effective tool to detect critical congenital heart disease (CCHD) in asymptomatic term infants, but its value in the neonatal intensive care unit (NICU) requires further clarification.
STUDY DESIGN
A retrospective review of 1005 babies without previously diagnosed CCHD admitted to a level III NICU was performed to assess the risk for missed CCHD and performance of POS.
RESULT
Of the 1005 NICU patients, 812 had documented POS and none failed POS. In 812 patients, 547 had delayed POS because of the use of supplemental oxygen. In 259/812 patients, POS was delayed until the baby was >2 weeks old. CCHD was excluded by echocardiography, irrespective of POS, in 287/1005 patients.
CONCLUSION
POS can be performed in the NICU with minimal adverse effects. However, in many NICU patients CCHD is confirmed or excluded before POS, and POS will frequently be performed after CCHD would have been expected to become symptomatic.
目的
脉搏血氧饱和度筛查（POS）是检测无症状足月儿严重先天性心脏病（CCHD）的有效工具，但其在新生儿重症监护病房（NICU）中的价值尚需进一步明确。
研究设计
对1005名入住三级NICU且此前未诊断出CCHD的婴儿进行回顾性研究，以评估漏诊CCHD的风险及POS的效能。
结果
1005名NICU患者中，812名有POS记录且无一例POS筛查失败。在812名患者中，547名因使用补充氧气而延迟进行POS。在259/812名患者中，POS延迟至婴儿超过2周龄。1005名患者中有287名经超声心动图排除了CCHD，无论其POS结果如何。
结论
在NICU中进行POS的不良反应最小。然而，许多NICU患者在进行POS之前CCHD已被确诊或排除，且POS常常在CCHD预计出现症状之后进行。
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