通过对液体分布模式的超声评估来确定胎儿水肿的病因
Confirmation of etiology in fetal hydrops by sonographic evaluation of fluid allocation patterns.
作者信息
Hartge David R, Weichert Jan, Gembicki Michael, Krapp Martin
机构信息
Dept. of Prenatal Medicine, University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
Dept. of Prenatal Medicine, University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
出版信息
Eur J Obstet Gynecol Reprod Biol. 2015 Dec;195:128-132. doi: 10.1016/j.ejogrb.2015.09.006. Epub 2015 Oct 19.
OBJECTIVE
To evaluate patterns of fluid allocations in different etiologies of hydrops fetalis.
STUDY DESIGN
This report is a retrospective cohort study on 20,395 fetal sonographic evaluations in a single tertiary center from 2000 to 2014. Special emphasis was placed on the exact description of the distinct fluid allocation sites in each fetus. Postmortem/postnatal records were evaluated additionally. Mean follow up of the surviving neonates was 34 days (10-60 days).
RESULTS
There seem to be distinctive patterns of fluid allocation in some etiologies leading to fetal hydrops including aneuploidies and Parvovirus B19 related infections.
CONCLUSION
Due to the allocation patterns of fluid filled sites in fetuses with hydrops fetalis the spectrum of possible etiologies may be narrowed already during initial ultrasound scan. It can contribute substantially to diagnostic accuracy as well as to parental counseling. This knowledge may also help to omit delay in diagnostic routines.
目的
评估胎儿水肿不同病因中的液体分布模式。
研究设计
本报告是一项回顾性队列研究，对2000年至2014年在单一三级中心进行的20395例胎儿超声评估进行了研究。特别强调了对每个胎儿不同液体分布部位的精确描述。此外，还评估了死后/出生后的记录。存活新生儿的平均随访时间为34天（10 - 60天）。
结果
在一些导致胎儿水肿的病因中，包括非整倍体和细小病毒B19相关感染，似乎存在独特的液体分布模式。
结论
由于胎儿水肿胎儿中充满液体部位的分布模式，在初次超声扫描时，可能病因的范围就已经可以缩小。这对诊断准确性以及对父母的咨询都有很大帮助。这些知识也可能有助于避免诊断程序的延迟。
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