Mitchell Thomas A, Wallum Timothy E, White Christopher E, Sanders Kelly E, Aden James K, Bailey Jeffrey A, Blackbourne Lorne H, Murray Clinton K
San Antonio Military Medical Center Department of General Surgery, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, TX 78234.
United States Army Institute of Surgical Research, 3698 Chambers Pass STE B, JBSA Fort Sam Houston, TX 78234-7767.
Mil Med. 2015 Nov;180(11):1170-7. doi: 10.7205/MILMED-D-14-00295.
Postsplenectomy vaccination (PSV) in an austere environment to minimize overwhelming postsplenectomy infection is challenging. We evaluated the clinical impact of a March 2008 clinical practice guideline (CPG) dictating immediate PSV at North American Treaty Organization Role 3 medical treatment facilities and subsequent complications.
Utilizing U.S. military medical databases, we characterized all U.S. patients with a splenic injury from November 2002 to January 2012 by their surgical management: laparotomy with splenectomy (LWS), laparotomy without splenectomy, or nonoperative management. Relevant data including demographics, vaccinations, and documented bacterial and fungal isolates were obtained.
LWS comprised 63.6% of the 409 patients with a splenic injury from 2002 to 2012. The implementation of the PSV CPG improved overall vaccination compliance from 48.9% pre-PSV CPG to 86.9% post-PSV CPG (p < 0.01). It was found that 1.3% (2/159) of completely vaccinated LWS patients compared with 0% (0/101) of the incompletely vaccinated LWS patients had Streptococcus pneumoniae isolates in 391.0 and 251.4 follow-up years, respectively (p = 0.52). No Neisseria meningitidis or Haemophilus influenzae isolates were identified.
PSV CPG implementation improved theater vaccination without increasing the incidence of encapsulated organisms.
