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[Maspin和Ki67在结外鼻型NK/T细胞淋巴瘤中的表达及意义]

[Expressions of Maspin and Ki67 in extranodal nasal type NK/T-cell lymphoma and the significance].

作者信息

Hong Fei, Sun Jingwu, Li Chuanying, Wang Xiaoqiu, Chen Jingjing, Gu Ping

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jul;29(13):1184-6.

PMID:26540920
Abstract

OBJECTIVE

To analyze the expression of Maspin and Ki67 in EN-NK/TCL and the significance.

METHOD

The expressions of Maspin and Ki67 were detected by immunohistochemistry in 34 cases of EN-NK/TCL and 11 cases of chronic sinusitis.

RESULT

Maspin was low expressed in EN-NK/TCL, Ki67 was highly expressed in EN-NK/TCL. Negative correlation was found between the expression of Maspin and Ki67 in EN-NK/TCL.

CONCLUSION

The combined examination of Maspin and Ki67 has important significance in the diagnosis in EN-NK/ TCL.

摘要

目的

分析Maspin和Ki67在鼻腔鼻窦自然杀伤细胞/T细胞淋巴瘤（EN-NK/TCL）中的表达情况及其意义。

方法

采用免疫组织化学法检测34例EN-NK/TCL及11例慢性鼻窦炎患者中Maspin和Ki67的表达。

结果

Maspin在EN-NK/TCL中低表达，Ki67在EN-NK/TCL中高表达。EN-NK/TCL中Maspin与Ki67的表达呈负相关。

结论

Maspin和Ki67联合检测对EN-NK/TCL的诊断具有重要意义。

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