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1999 - 2014年台湾地区政府对在一个先前指定为无狂犬病岛屿上发现狂犬病病毒储存宿主物种的应对措施

Government Response to the Discovery of a Rabies Virus Reservoir Species on a Previously Designated Rabies-Free Island, Taiwan, 1999-2014.

作者信息

Chang S-S, Tsai H-J, Chang F-Y, Lee T-S, Huang K-C, Fang K-Y, Wallace R M, Inoue S, Fei C-Y

机构信息

Bureau of Animal and Plant Health Inspection and Quarantine, Council of Agriculture, Taipei, Taiwan.

Animal Health Research Institute, Council of Agriculture, Taipei, Taiwan.

出版信息

Zoonoses Public Health. 2016 Aug;63(5):396-402. doi: 10.1111/zph.12240. Epub 2015 Nov 6.

Abstract

Taiwan had been considered rabies free since 1961. In 2013, Taiwan confirmed the detection of rabies virus in wild Taiwan ferret-badgers. Up to December 2014, there have been 423 rabies-confirmed ferret-badgers and three cases of spillover infection into non-reservoir hosts. Genetic analysis indicates that TFBV is distinct from all other known rabies virus variants. To date, ferret-badger rabies is known to occur only in China and Taiwan. The temporal dynamics of rabid ferret-badgers in Taiwan suggests that the epizootic appears to have subsided to enzootic levels as of December 2014. According to the current epidemiologic data, there is only one TFBV strain in Taiwan. TFBV is still sequestered to the mountainous regions. Humans are at risk mainly through exposure to the virus from infected domestic meso-carnivores, mainly dogs and cats. Dogs and cats should be vaccinated to establish an immunological barrier to stop the spread of the disease from mountainous regions to domestic meso-carnivores.

摘要

自1961年以来,台湾一直被认为没有狂犬病。2013年,台湾证实检测到野生台湾鼬獾感染狂犬病病毒。截至2014年12月,已有423只鼬獾确诊感染狂犬病,并有3例病毒外溢感染非贮存宿主的病例。基因分析表明,台湾鼬獾狂犬病病毒(TFBV)与所有其他已知的狂犬病病毒变种不同。迄今为止,已知鼬獾狂犬病仅在中国和台湾发生。台湾狂犬病鼬獾的时间动态表明,截至2014年12月,该流行病似乎已降至地方病水平。根据目前的流行病学数据,台湾只有一种TFBV毒株。TFBV仍局限于山区。人类主要通过接触受感染的家养中食肉动物(主要是狗和猫)携带的病毒而面临风险。狗和猫应接种疫苗,建立免疫屏障,以阻止疾病从山区传播到家养中食肉动物。

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