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地西他滨治疗后出现的手足综合征。

Hand-foot syndrome following decitabine.

作者信息

Ali Alaa M, Jacoby Meagan, Welch John S

机构信息

Division of Hospital Medicine, Washington University School of Medicine, St. Louis, USA.

Division of Oncology, Stem Cell Biology Section, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8007, St. Louis, MO, 63110, USA.

出版信息

Ann Hematol. 2016 Feb;95(3):535-6. doi: 10.1007/s00277-015-2546-1. Epub 2015 Nov 6.

DOI:10.1007/s00277-015-2546-1
PMID:26542147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5175272/
Abstract

We observed a case of Hand-Foot Syndrome (HFS) in a patient treated with decitabine. HFS has not previously been associated with decitabine, although it has been observed following treatment with the structurally similar pyrimidine analogue cytarabine.

摘要

我们观察到1例接受地西他滨治疗的患者发生了手足综合征（HFS）。尽管在使用结构相似的嘧啶类似物阿糖胞苷治疗后曾观察到HFS，但此前HFS与地西他滨并无关联。

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Hand-foot syndrome following decitabine.地西他滨治疗后出现的手足综合征。
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本文引用的文献

1
Results of phase 2 randomized study of low-dose decitabine with or without valproic acid in patients with myelodysplastic syndrome and acute myelogenous leukemia.低剂量地西他滨联合或不联合丙戊酸治疗骨髓增生异常综合征和急性髓系白血病的 2 期随机研究结果。
Cancer. 2015 Feb 15;121(4):556-61. doi: 10.1002/cncr.29085. Epub 2014 Oct 21.
2
Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia.多中心、随机、开放标签、III 期临床试验，比较地西他滨与患者选择的支持治疗或低剂量阿糖胞苷治疗新诊断的老年急性髓系白血病，患者选择方案由医生提供建议。
J Clin Oncol. 2012 Jul 20;30(21):2670-7. doi: 10.1200/JCO.2011.38.9429. Epub 2012 Jun 11.
3
HFS-14, a specific quality of life scale developed for patients suffering from hand-foot syndrome.HFS-14，一种专为手足综合征患者开发的特定生活质量量表。
Oncologist. 2011;16(10):1469-78. doi: 10.1634/theoncologist.2011-0033. Epub 2011 Sep 30.
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The hand-foot-syndrome associated with medical tumor therapy - classification and management.医学肿瘤治疗相关手足综合征 - 分类与管理。
J Dtsch Dermatol Ges. 2010 Sep;8(9):652-61. doi: 10.1111/j.1610-0387.2010.07449.x. Epub 2010 May 6.
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Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.手足综合征（手足皮肤反应，掌跖红斑感觉不良）：重点关注索拉非尼和舒尼替尼。
Oncology. 2009;77(5):257-71. doi: 10.1159/000258880. Epub 2009 Nov 16.
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