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Decitabine studies in chronic and acute myelogenous leukemia.

作者信息

Kantarjian H M, O'Brien S M, Estey E, Giralt S, Beran M, Rios M B, Keating M, de Vos D, Talpaz M

机构信息

MD Anderson Cancer Center, Department of Hematology, Houston, Texas 77030, USA.

出版信息

Leukemia. 1997 Mar;11 Suppl 1:S35-6.

PMID:9130691
Abstract
摘要

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Decitabine studies in chronic and acute myelogenous leukemia.地西他滨在慢性和急性髓性白血病中的研究。
Leukemia. 1997 Mar;11 Suppl 1:S35-6.
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Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia.130例慢性粒细胞白血病患者接受地西他滨（5-氮杂-2'-脱氧胞苷）治疗的结果。
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Decitabine improves outcomes in older patients with acute myeloid leukemia and higher blast counts.地西他滨可改善急性髓性白血病且原始细胞计数较高的老年患者的预后。
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Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia.地西他滨治疗慢性粒细胞白血病加速期和急变期的结果。
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[5-day decitabine for treatment of myelodysplastic syndromes with complex karyotype abnormalities and acute myeloid leukemia].5天阿扎胞苷治疗伴有复杂核型异常的骨髓增生异常综合征及急性髓系白血病
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Epigenetic therapies in MDS and AML.骨髓增生异常综合征和急性髓系白血病的表观遗传学治疗。
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Treatment options in advanced myelodysplastic syndrome, with emphasis on epigenetic therapy.晚期骨髓增生异常综合征的治疗选择，重点是表观遗传治疗。
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Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells.DNA甲基转移酶的抑制作用可刺激结肠肿瘤细胞中信号转导及转录激活因子1、2和3基因的表达。
Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):14007-12. doi: 10.1073/pnas.96.24.14007.