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大脑常染色体显性动脉病伴皮质下梗死和白质脑病患者大脑中动脉狭窄的颞浅动脉-大脑中动脉搭桥手术

Superficial temporal artery-to-middle cerebral artery bypass surgery for middle cerebral artery stenosis in a patient with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

作者信息

Muta Daisuke, Kawano Takayuki, Shinojima Naoki, Kuratsu Junichi

机构信息

Department of Neurosurgery, Kumamoto University Graduate School of Medical Sciences, 1-1-1 Honjyo, Chuoku, Kumamoto, 8608556 Japan.

出版信息

Springerplus. 2015 Oct 14;4:609. doi: 10.1186/s40064-015-1407-7. eCollection 2015.

Abstract

Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy is a rare hereditary small vessel disease. Ischemic events are the main clinical manifestation of this condition. Here, we present a case in which superficial temporal artery-to-middle cerebral artery anastomosis was performed in a patient with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy who developed cerebral infarctions caused by severe middle cerebral artery stenosis. Cerebral blood flow and cerebrovascular reactivity were effectively improved using double anastomoses. To our knowledge, surgical revascularization for patients with this condition has not yet been described in the literature. Superficial temporal artery-to-middle cerebral artery anastomosis is effective for patients with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy who show marked regional cerebral hypoperfusion.

摘要

伴有皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病是一种罕见的遗传性小血管疾病。缺血性事件是该疾病的主要临床表现。在此,我们报告一例伴有皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病患者,因大脑中动脉严重狭窄导致脑梗死,对其实施了颞浅动脉-大脑中动脉吻合术。通过双重吻合有效地改善了脑血流和脑血管反应性。据我们所知,文献中尚未描述针对该疾病患者的手术血运重建。颞浅动脉-大脑中动脉吻合术对伴有皮质下梗死和白质脑病且表现出明显局部脑灌注不足的常染色体显性遗传性脑动脉病患者有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb78/4628037/c889581910ab/40064_2015_1407_Fig1_HTML.jpg

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