Fukutomi T, Nanasawa T, Yamamoto H
Dept. of Surgery, National Cancer Center Hospital.
Gan No Rinsho. 1989 Apr;35(5):575-9.
We have studied influences from the treatment of a thyroid disease and diabetes mellitus on breast cancer prognosis. Forty-one breast cancer patients with a thyroid disease and 16 cases with diabetes mellitus under medical treatment have been investigated. There was no special clinicopathological characteristics found in patients with a thyroid disease. The 5-year relapse-free survival rate (5 Y-RFS) of these patients was 95% and the 5-year overall survival rate (5 Y-OS) was 100%. Therefore, the presence of a thyroid disease showed no significant effect on the survival of breast cancer patients. In contrast, the prognosis of a group of diabetes mellitus was relatively poor, the 5 Y-RFS showing 75% and 5 Y-OS 81%. A significantly worse survival rate was found in cases of insulin treated subgroups compared to orally treated patients.
我们研究了甲状腺疾病和糖尿病的治疗对乳腺癌预后的影响。对41例患有甲状腺疾病的乳腺癌患者和16例正在接受治疗的糖尿病患者进行了调查。在患有甲状腺疾病的患者中未发现特殊的临床病理特征。这些患者的5年无复发生存率（5 Y-RFS）为95%，5年总生存率（5 Y-OS）为100%。因此，甲状腺疾病的存在对乳腺癌患者的生存没有显著影响。相比之下，一组糖尿病患者的预后相对较差，5 Y-RFS为75%，5 Y-OS为81%。与口服治疗的患者相比，胰岛素治疗亚组的生存率明显更差。
