Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile; FONDAP Center for Geroscience, Brain Health and Metabolism, University of Chile, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston MA 02115, USA.
Cell. 2015 Nov 5;163(4):790-1. doi: 10.1016/j.cell.2015.10.060.
Pejvakin (PJVK), a protein originally identified in Persian families with sensorineural hearing loss, regulates peroxisomal dynamics and the antioxidant defense triggered by noise exposure in hair cells and auditory neurons of the inner ear. These findings bring peroxisomes to the forefront of noise-induced hearing loss research.
佩吉瓦金（PJVK）是一种最初在患有感觉神经性听力损失的波斯裔家族中发现的蛋白，它调节过氧化物酶体的动态平衡，并在毛细胞和内耳听觉神经元中由噪声暴露引发的抗氧化防御反应。这些发现使过氧化物酶体成为噪声性听力损失研究的焦点。
