Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice.
作者信息
Valverde Yessenia, Benson Barbara, Gupta Mihir, Gupta Kalpna
机构信息
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN.
Department of Neurosurgery, University of California San Diego, La Jolla, CA, USA.
出版信息
Haematologica. 2016 Feb;101(2):e44-7. doi: 10.3324/haematol.2015.137489. Epub 2015 Nov 6.
Abstract
摘要
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Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice.姜黄素或辅酶Q治疗可减轻镰状小鼠的脊髓胶质细胞激活和氧化应激。
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PLoS One. 2015 Jul 31;10(7):e0134156. doi: 10.1371/journal.pone.0134156. eCollection 2015.
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Intrathecal curcumin attenuates pain hypersensitivity and decreases spinal neuroinflammation in rat model of monoarthritis.鞘内注射姜黄素可减轻单关节炎大鼠模型的疼痛超敏反应并降低脊髓神经炎症。
Sci Rep. 2015 May 19;5:10278. doi: 10.1038/srep10278.
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Morphine for the treatment of pain in sickle cell disease.吗啡用于治疗镰状细胞病的疼痛。
ScientificWorldJournal. 2015;2015:540154. doi: 10.1155/2015/540154. Epub 2015 Jan 12.
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Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease.在镰状细胞病的转基因模型中，伤害性脊髓神经元的敏化会导致疼痛。
Pain. 2015 Apr;156(4):722-730. doi: 10.1097/j.pain.0000000000000104.
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Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study.高生物利用度姜黄素治疗膝骨关节炎的短期疗效：一项随机、双盲、安慰剂对照的前瞻性研究。
J Orthop Sci. 2014 Nov;19(6):933-9. doi: 10.1007/s00776-014-0633-0. Epub 2014 Oct 13.
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Pathological pain and the neuroimmune interface.病理性疼痛与神经免疫界面。
Nat Rev Immunol. 2014 Apr;14(4):217-31. doi: 10.1038/nri3621. Epub 2014 Feb 28.
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Hematological Parameters and RBC TBARS Level of Q 10 Supplemented Tribal Sickle Cell Patients: A Hospital Based Study.补充辅酶Q10的部落镰状细胞病患者的血液学参数及红细胞丙二醛水平：一项基于医院的研究
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Mast cell activation contributes to sickle cell pathobiology and pain in mice.肥大细胞活化导致小鼠镰状细胞病理和疼痛。
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Therapeutic roles of curcumin: lessons learned from clinical trials.姜黄素的治疗作用：临床试验获得的经验。
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