Singla Navneet, Dhandapani S S, Kapoor Ankur, Chatterjee Debajyoti, Vashishta R K
Post Graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India.
Post Graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India.
J Clin Neurosci. 2016 Mar;25:147-50. doi: 10.1016/j.jocn.2015.05.058. Epub 2015 Nov 4.
Astroblastoma is a rare tumor of glial origin with characteristics of both astrocytoma and ependymoma. It is usually seen in children and young adults, and is peripherally located, well circumscribed, of solid-cystic composition and with heterogeneous contrast enhancement. Histopathology reveals perivascular pseudorosette formation and thick hyalinised vessels. Hemorrhage in astroblastoma is unusual and rarely described in literature. We report two patients with astroblastoma who presented with hemorrhage and discuss the natural history, radiological findings, pathophysiology of hemorrhage and histopathological characteristics. We emphasize the importance of early suspicion in peripherally located lesions with bleeding.
星形母细胞瘤是一种起源于神经胶质的罕见肿瘤，具有星形细胞瘤和室管膜瘤的特征。它通常见于儿童和年轻人，位于外周，边界清晰，由实性和囊性成分组成，增强扫描呈不均匀强化。组织病理学显示血管周围假菊形团形成和厚壁玻璃样变血管。星形母细胞瘤出血并不常见，文献中鲜有描述。我们报告了两名出现出血症状的星形母细胞瘤患者，并讨论了其自然病史、影像学表现、出血的病理生理学及组织病理学特征。我们强调对于外周出现出血性病变早期怀疑的重要性。
