Roche Lisa M, Niu Xiaoling, Henry Kevin A
J Health Care Poor Underserved. 2015 Nov;26(4):1173-85. doi: 10.1353/hpu.2015.0127.
Although invasive cervical cancer incidence has declined, disparities persist. We identified spatial clusters of census tracts with elevated invasive cervical cancer incidence rates using New Jersey State Cancer Registry cases 20 years or older diagnosed in 2005-2009. Each cluster's population was compared with the rest of New Jersey's population on demographic and socioeconomic characteristics. Odds ratios that assessed associations between statistically significant characteristics (from a univariate comparison of cases in the clusters versus cases in the rest of New Jersey) and being a case in a cluster versus being a case in the rest of New Jersey were calculated from logistic regression models. Significant incidence clusters were identified around Newark, Trenton, and Camden. Being Black (all areas), Hispanic (Newark, Camden), unmarried (Newark), and uninsured/Medicaid-insured (Trenton) were significantly associated with being a case in these areas. These study results can be used to target invasive cervical cancer prevention efforts more effectively.
尽管浸润性宫颈癌的发病率有所下降，但差异依然存在。我们利用2005 - 2009年新泽西州癌症登记处确诊的20岁及以上病例，确定了浸润性宫颈癌发病率升高的普查区空间聚集情况。将每个聚集区的人口与新泽西州其他人口在人口统计学和社会经济特征方面进行比较。通过逻辑回归模型计算优势比，评估统计学上显著特征（来自聚集区病例与新泽西州其他地区病例的单变量比较）与在聚集区为病例与在新泽西州其他地区为病例之间的关联。在纽瓦克、特伦顿和卡姆登周围发现了显著的发病聚集区。黑人（所有地区）、西班牙裔（纽瓦克、卡姆登）、未婚（纽瓦克）以及未参保/参加医疗补助保险（特伦顿）与这些地区的发病情况显著相关。这些研究结果可用于更有效地针对浸润性宫颈癌预防工作。
