Ashino Sonoko, Nakai Toshiko, Sonoda Kazumasa, Sasaki Naoko, Kurokawa Sayaka, Ikeya Yukitoshi, Okumura Yasuo, Ohkubo Kimie, Kunimoto Satoshi, Watanabe Ichiro, Hirayama Atsushi
Division of Cardiology, Department of Medicine, Nihon University School of Medicine.
Int Heart J. 2015;56(6):618-21. doi: 10.1536/ihj.15-093. Epub 2015 Nov 6.
Defibrillation threshold (DFT) testing is performed routinely in patients undergoing implantable cardioverter-defibrillator (ICD) implantation to verify the ability of the ICD to terminate ventricular fibrillation (VF). However, neither the efficacy nor the safety of DFT testing has been proven; thus, the necessity of such testing is controversial. We conducted a retrospective study of the efficacy of DFT testing, particularly with respect to long-term outcomes of ICD implantation.The study included 150 patients (125 men, 25 women, aged 59.0 ± 17.6 years) who underwent ICD or cardiac resynchronization therapy defibrillator implantation, with (n = 73) or without (n = 77) intraoperative DFT testing, between June 1996 and September 2007. VF was induced by delivery of a T-wave shock, and a 20-25-J shock was then delivered. If the 20-25-J shock failed to terminate VF, 30 J was delivered. We assessed whether undersensed VF events occurred during DFT testing and/or during patient follow-up and checked for any association between undersensing and delayed shock delivery. During DFT testing, fine VF was sensed, and shocks were delivered in a timely manner. Nevertheless, 2 patients in the DFT testing group died from VF within 3 years after device implantation.DFT testing, in comparison to non-DFT testing, appeared to have no influence on the long-term outcomes of our patients, suggesting that DFT testing at the time of ICD implantation is limited.
在接受植入式心脏复律除颤器(ICD)植入的患者中,常规进行除颤阈值(DFT)测试,以验证ICD终止心室颤动(VF)的能力。然而,DFT测试的有效性和安全性均未得到证实;因此,此类测试的必要性存在争议。我们对DFT测试的有效性进行了一项回顾性研究,特别是关于ICD植入的长期结果。该研究纳入了1996年6月至2007年9月期间接受ICD或心脏再同步治疗除颤器植入的150例患者(125例男性,25例女性,年龄59.0±17.6岁),其中73例进行了术中DFT测试,77例未进行。通过发放T波电击诱发VF,然后发放20 - 25焦耳的电击。如果20 - 25焦耳的电击未能终止VF,则发放30焦耳的电击。我们评估了在DFT测试期间和/或患者随访期间是否发生感知不足的VF事件,并检查了感知不足与电击延迟发放之间的任何关联。在DFT测试期间,可感知到细微的VF,且电击及时发放。尽管如此,DFT测试组中有2例患者在装置植入后3年内死于VF。与非DFT测试相比,DFT测试似乎对我们患者的长期结果没有影响,这表明ICD植入时的DFT测试作用有限。