Renfordt E
Department of Psychiatry, Free University of Berlin, West, Germany.
Pharmacopsychiatry. 1989 Feb;22 Suppl 1:2-4. doi: 10.1055/s-2007-1014616.
The reduced speech activity of depressed patients is a consistent finding in many systematic studies. However, this and other nonverbal parameters have seldom been investigated in psychopharmacological studies. In this double-blind study, 21 retarded depressed patients were treated with amitriptyline or pirlindol over a four-week period. The speech behavior of the patients was analyzed by computer techniques, and the drug-induced changes in these variables were compared with the psychopathological effects of the treatment.
抑郁症患者言语活动减少是许多系统性研究中一致的发现。然而，在精神药理学研究中，这一以及其他非言语参数很少被研究。在这项双盲研究中，21名迟滞性抑郁症患者在四周时间内接受了阿米替林或匹克隆的治疗。通过计算机技术分析患者的言语行为，并将这些变量的药物诱导变化与治疗的精神病理学效果进行比较。
