蒌叶（槟榔叶）各种药用特性的潜在作用机制。

The underlying mechanism of action for various medicinal properties of Piper betle (betel).

作者信息

Haslan H, Suhaimi F H, Thent Zar Chi, Das S

机构信息

Department of Anatomy, 18th Floor, Pre-Clinical Block, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia - Anatomy Unit, Faculty of Medicine, UiTM Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor Darul Ehsan.

Department of Anatomy, 18th Floor, Pre-Clinical Block, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia.

出版信息

Clin Ter. 2015;166(5):208-14. doi: 10.7417/CT.2015.1880.

DOI:10.7417/CT.2015.1880

PMID:26550811

Abstract

Piper betle (betel) plant belongs to the Piperaceae family. Piper. betle is widely known for its potent medicinal properties. Various active compounds are present in Piper. betle such as allylpyrocatechol, hydroxychavicol, piperbetol, ethylpiperbetol, piperol A, piperol B, chavibetol, and alkaloids which account for these beneficial medicinal properties. In the present narrative review, we looked into the various active compounds present in the Piper betle and attempted to understand their underlying mechanism of action. Proper understanding of the molecular biology involving the mechanism of action may help in better drug formulation and provide better therapeutic actions in the field of alternative and complementary medicine.

摘要

蒌叶属于胡椒科。蒌叶因其强大的药用特性而广为人知。蒌叶中存在多种活性化合物，如烯丙基邻苯二酚、羟基查维酮、胡椒醇、乙基胡椒醇、胡椒酚A、胡椒酚B、异丁子香酚，以及赋予这些有益药用特性的生物碱。在本叙述性综述中，我们研究了蒌叶中存在的各种活性化合物，并试图了解其潜在的作用机制。对涉及作用机制的分子生物学的正确理解可能有助于更好地进行药物配方，并在替代医学和补充医学领域提供更好的治疗效果。