Deng Gai-Gai, Yang Xiu-Wei, Zhang You-Bo, Xu Wei, Wei Wei, Chen Tian-Li
Zhongguo Zhong Yao Za Zhi. 2015 Jun;40(11):2148-56.
The chemical constituents from lipophilic parts in the roots of Angelica dahurica var. formosana cv. Chuanbaizhi were studied in this paper. The compounds were separated and purified by repeated column chromatographic methods on silica gel and HPLC, and the chemical structures of compounds were determined by spectral data analyses. Twenty-nine compounds were obtained and identified as isoimperatorin (1), β-sitosterol (2), imperatorin (3), bergapten (4), osthenol (5), xanthotoxin (6), isoimpinellin (7), dehydrogeijerin (8), phellopterin (9), isodemethylfuropinarine (10), 7-demethylsuberosin (11), alloimperatorin (12), xanthotoxol (13), isooxypeucedanin (14), alloisoimperatorin (15), demethylfuropinarine (16), 5-hydroxy-8-methoxypsoralen (17), oxypeucedanin methanolate (18), pabulenol (19), byakangelicin (20), marmesin (21), (+) -decursinol (22), heraclenol (23), oxypeucedanin hydrate (24), marmesinin (25), ulopterol (26), erythro-guaiacylglycerol-β-ferulic acid ether (27), threo-guaiacylglycerol-β-ferulic acid ether (28), and uracil (29). Compounds 5, 8, 11, 18, 21-23, and 26-28 were obtained from the roots of title plant for the first time.
本文对台湾当归变种川芎白芷根中亲脂性部位的化学成分进行了研究。通过硅胶柱色谱和高效液相色谱等反复柱色谱方法对化合物进行分离纯化,并通过光谱数据分析确定化合物的化学结构。共获得29个化合物,分别鉴定为异欧前胡素(1)、β-谷甾醇(2)、欧前胡素(3)、佛手柑内酯(4)、蛇床子素(5)、花椒毒素(6)、异茴芹内酯(7)、去氢欧芹属素乙(8)、紫花前胡素(9)、异去甲基补骨脂素(10)、7-去甲基异紫花前胡内酯(11)、别欧前胡素(12)、花椒毒酚(13)、异氧化前胡素(14)、异别欧前胡素(15)、去甲基补骨脂素(16)、5-羟基-8-甲氧基补骨脂素(17)、氧化前胡素甲醇化物(18)、杷贝醇(19)、白花前胡丙素(20)、豆甾醇(21)、(+)-紫花前胡醇(22)、独活醇(23)、氧化前胡素水合物(24)、豆甾醇苷(25)、翅茎香青素(26)、赤式-愈创木基甘油-β-阿魏酸醚(27)、苏式-愈创木基甘油-β-阿魏酸醚(28)和尿嘧啶(29)。化合物5、8、11、18、21 - 23以及26 - 28首次从该植物根中获得。