McKinnon Britt, Yang Seungmi, Kramer Michael S, Bushnik Tracey, Sheppard Amanda J, Kaufman Jay S
Department of Epidemiology, Biostatistics and Occupational Health (McKinnon, Yang, Kramer, Kaufman), McGill University Faculty of Medicine, Montréal, Que.; Institute for Health and Social Policy (McKinnon, Kaufman), McGill University, Montréal, Que.; Department of Pediatrics (Kramer), McGill University Faculty of Medicine, Montréal, Que.; Health Analysis Division (Bushnik), Statistics Canada, Ottawa, Ont.; AboutKidsHealth (Sheppard), The Hospital for Sick Children, Toronto, Ont.; Dalla Lana School of Public Health (Sheppard), University of Toronto, Toronto, Ont.
CMAJ. 2016 Jan 5;188(1):E19-E26. doi: 10.1503/cmaj.150464. Epub 2015 Nov 9.
A higher risk of preterm birth among black women than among white women is well established in the United States. We compared differences in preterm birth between non-Hispanic black and white women in Canada and the US, hypothesizing that disparities would be less extreme in Canada given the different historical experiences of black populations and Canada's universal health care system.
Using data on singleton live births in Canada and the US for 2004-2006, we estimated crude and adjusted risk ratios and risk differences in preterm birth (< 37 wk) and very preterm birth (< 32 wk) among non-Hispanic black versus non-Hispanic white women in each country. Adjusted models for the US were standardized to the covariate distribution of the Canadian cohort.
In Canada, 8.9% and 5.9% of infants born to black and white mothers, respectively, were preterm; the corresponding figures in the US were 12.7% and 8.0%. Crude risk ratios for preterm birth among black women relative to white women were 1.49 (95% confidence interval [CI] 1.32 to 1.66) in Canada and 1.57 (95% CI 1.56 to 1.58) in the US (p value for heterogeneity [pH] = 0.3). The crude risk differences for preterm birth were 2.94 (95% CI 1.91 to 3.96) in Canada and 4.63 (95% CI 4.56 to 4.70) in the US (pH = 0.003). Adjusted risk ratios for preterm birth (pH = 0.1) were slightly higher in Canada than in the US, whereas adjusted risk differences were similar in both countries. Similar patterns were observed for racial disparities in very preterm birth.
Relative disparities in preterm birth and very preterm birth between non-Hispanic black and white women were similar in magnitude in Canada and the US. Absolute disparities were smaller in Canada, which reflects a lower overall risk of preterm birth in Canada than in the US in both black and white populations.
在美国,黑人女性比白人女性有更高的早产风险,这一点已得到充分证实。我们比较了加拿大和美国非西班牙裔黑人和白人女性之间早产情况的差异,推测鉴于黑人人口不同的历史经历以及加拿大的全民医疗保健系统,加拿大的差异不会那么极端。
利用2004 - 2006年加拿大和美国单胎活产的数据,我们估计了每个国家非西班牙裔黑人与非西班牙裔白人女性早产(<37周)和极早产(<32周)的粗风险比和调整风险比以及风险差异。美国的调整模型根据加拿大队列的协变量分布进行了标准化。
在加拿大,黑人母亲和白人母亲所生婴儿的早产率分别为8.9%和5.9%;在美国,相应数字分别为12.7%和8.0%。加拿大黑人女性相对于白人女性的早产粗风险比为1.49(95%置信区间[CI]1.32至1.66),美国为1.57(95%CI 1.56至1.58)(异质性p值[pH]=0.3)。加拿大早产的粗风险差异为2.94(95%CI 1.91至3.96),美国为4.63(95%CI 4.56至4.70)(pH = 0.003)。加拿大早产的调整风险比(pH = 0.1)略高于美国,而两国的调整风险差异相似。在极早产的种族差异方面也观察到类似模式。
加拿大和美国非西班牙裔黑人和白人女性之间早产和极早产的相对差异在程度上相似。加拿大的绝对差异较小,这反映出加拿大黑人和白人人口的总体早产风险低于美国。